General Structure Information
| PDB ID | 2fmm |
| HGNC Gene Label(s) | C11orf30 |
| Structure Name | crystal structure of emsy-hp1 complex |
| Resolution | 1.8Å |
| Reference | AUTH Y.HUANG,M.P.MYERS,R.M.XUTITL CRYSTAL STRUCTURE OF THE HP1-EMSY COMPLEX REVEALS AN UNUSUALTITL 2 MODE OF HP1 BINDING.REF STRUCTURE V. 14 703 2006REFN ISSN 0969-2126PMID 16615912DOI 10.1016/J.STR.2006.01.007 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 116 |
| Number Of SNVs | 24 |
| Number Of Permutations | 29317 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.12 |
| p-value | 0.15 |
COSMIC
| Number Of Residues | 116 |
| Number Of SNVs | 4 |
| Number Of Permutations | 267 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | 0.167 |
| p-value | 0.348 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 24 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | -0.301 |
| p-value | 0.263 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
