4H22.A | LRRFIP1

PDB ID	4h22
HGNC Gene Label(s)	LRRFIP1
Structure Name	crystal structure of the dimeric coiled-coil domain of the cytosolic nucleic acid sensor lrrfip1
Resolution	2.89Å
Reference	AUTH J.B.NGUYEN,Y.MODISTITL CRYSTAL STRUCTURE OF THE DIMERIC COILED-COIL DOMAIN OF THETITL 2 CYTOSOLIC NUCLEIC ACID SENSOR LRRFIP1.REF J.STRUCT.BIOL. V. 181 82 2013REFN ISSN 1047-8477PMID 23099021DOI 10.1016/J.JSB.2012.10.006

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
2:238661983	rs183615425	K>R	A:172	(-45.95, 25.23, -46.17)
2:238661984		K>N	A:172	(-45.95, 25.23, -46.17)
2:238661991	rs200750365	M>V	A:175	(-40.70, 28.33, -45.02)
2:238662001	rs146344921	N>S	A:178	(-35.33, 26.60, -44.61)
2:238662021		K>E	A:185	(-26.45, 25.34, -39.04)
2:238662027		N>D	A:187	(-27.81, 20.94, -33.08)
2:238662048		T>A	A:194	(-18.55, 19.83, -27.15)
2:238662082	rs142734858	Q>R	A:205	(-5.81, 12.97, -20.30)
2:238662087		A>S	A:207	(0.56, 14.39, -22.22)
2:238662094		S>F	A:209	(0.64, 9.63, -19.86)
2:238662099		R>W	A:211	(4.88, 13.61, -17.27)
2:238662103		Q>R	A:212	(3.02, 9.47, -15.89)
2:238662106	rs186481410	Y>C	A:213	(7.12, 6.00, -20.53)
2:238662108	COSM282542 COSM282543	E>K	A:214	(9.56, 9.60, -20.43)
2:238664754		K>R	A:224	(18.43, -1.46, -14.53)
2:238664762	rs182477318	H>N	A:227	(20.26, -4.19, -8.82)
2:238664765	rs148114732	S>R	A:228	(24.29, -3.21, -10.96)
2:238664785		F>L	A:234	(26.46, -9.38, -2.35)
2:238664786		A>T	A:235	(30.21, -10.19, -4.95)
2:238664793		V>G	A:237	(31.37, -8.48, 0.48)
2:238664796		K>R	A:238	(29.50, -13.49, -1.41)
2:238664825		L>F	A:248	(36.01, -20.38, 11.32)

4H22.A | LRRFIP1.