Assessment of Structural Intolerance and Durability
General Structure Information 3ff7 KLRG1 structure of nk cell receptor klrg1 bound to e-cadherin 1.8Å AUTH Y.LI,M.HOFMANN,Q.WANG,L.TENG,L.K.CHLEWICKI,AUTH 2 H.PIRCHER,R.A.MARIUZZATITL STRUCTURE OF NATURAL KILLER CELL RECEPTOR KLRG1TITL 2 BOUND TO E-CADHERIN REVEALS BASIS FORTITL 3 MHC-INDEPENDENT MISSING SELF RECOGNITION.REF IMMUNITY V. 31 35 2009REFN ISSN 1074-7613PMID 19604491DOI 10.1016/J.IMMUNI.2009.04.019 Variant Set Distributions Mapped Variants
General Structure Information 3un9 NLRX1 crystal structure of an immune receptor 2.65Å AUTH M.HONG,S.I.YOON,I.A.WILSONTITL STRUCTURE AND FUNCTIONAL CHARACTERIZATION OF THE RNA-BINDINGTITL 2 ELEMENT OF THE NLRX1 INNATE IMMUNE MODULATOR.REF IMMUNITY V. 36 337 2012REFN ISSN 1074-7613PMID 22386589DOI 10.1016/J.IMMUNI.2011.12.018 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2nms CD300LF the crystal structure of the extracellular domain of the inhibitor receptor expressed on myeloid cells irem-1 2.6Å AUTH J.A.MARQUEZ,E.GALFRE,F.DUPEUX,D.FLOT,O.MORAN,AUTH 2 N.DIMASITITL THE CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAINTITL 2 OF THE INHIBITOR RECEPTOR EXPRESSED ON MYELOIDTITL 3 CELLS IREM-1.REF J.MOL.BIOL. V. 367 310 2007REFN ISSN 0022-2836PMID 17275839DOI 10.1016/J.JMB.2007.01.011 Variant Set […]
General Structure Information 2m1x TICAM1 ticam-1 tir domain structure -1.0Å AUTH Y.ENOKIZONO,H.KUMETA,K.FUNAMI,M.HORIUCHI,J.SARMIENTO,AUTH 2 K.YAMASHITA,D.M.STANDLEY,M.MATSUMOTO,T.SEYA,F.INAGAKITITL STRUCTURES AND INTERFACE MAPPING OF THE TIRTITL 2 DOMAIN-CONTAINING ADAPTOR MOLECULES INVOLVED IN INTERFERONTITL 3 SIGNALING.REF PROC.NATL.ACAD.SCI.USA V. 110 19908 2013REFN ISSN 0027-8424PMID 24255114DOI 10.1073/PNAS.1222811110 Variant Set Distributions Mapped Variants
General Structure Information 4hwn FCRLA crystal structure of the second ig-c2 domain of human fc-receptor like a (fcrla), isoform 9 [nysgrc-005836] 2.01Å AUTH P.R.KUMAR,S.G.NATHENSON,S.C.ALMOTITL CRYSTAL STRUCTURE OF THE SECOND IG-C2 DOMAIN OF THE HUMANTITL 2 FC-RECEPTOR LIKE A, ISOFORM 9 [NYSGRC-005836]REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 2frg TREML1 structure of the immunoglobulin-like domain of human tlt-1 1.19Å AUTH J.L.GATTIS,A.V.WASHINGTON,M.M.CHISHOLM,L.QUIGLEY,AUTH 2 A.SZYK,D.W.MCVICAR,J.LUBKOWSKITITL THE STRUCTURE OF THE EXTRACELLULAR DOMAIN OFTITL 2 TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLSTITL 3 LIKE TRANSCRIPT-1 AND EVIDENCE FOR A NATURALLYTITL 4 OCCURRING SOLUBLE FRAGMENT.REF J.BIOL.CHEM. V. 281 13396 2006REFN ISSN 0021-9258PMID 16505478DOI 10.1074/JBC.M600489200 Variant Set […]
General Structure Information 2x5y ZC3HAV1 human zc3hav1 (artd13), c-terminal domain 1.05Å AUTH T.KARLBERG,M.KLEPSCH,A.THORSELL,C.D.ANDERSSON,A.LINUSSON,AUTH 2 H.SCHULERTITL STRUCTURAL BASIS FOR LACK OF ADP-RIBOSYLTRANSFERASETITL 2 ACTIVITY IN POLY(ADP-RIBOSE) POLYMERASE-13/ZINC FINGERTITL 3 ANTIVIRAL PROTEIN.REF J.BIOL.CHEM. V. 290 7336 2015REFN ISSN 0021-9258PMID 25635049DOI 10.1074/JBC.M114.630160 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2cry KIRREL3 solution structure of the fifth ig-like domain of human kin of irre like 3 -1.0Å AUTH C.KUROSAKI,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIFTH IG-LIKE DOMAIN OFTITL 2 HUMAN KIN OF IRRE LIKE 3REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4gos VTCN1 crystal structure of human b7-h4 igv-like domain 1.59Å AUTH V.VIGDOROVICH,U.RAMAGOPAL,S.G.NATHENSON,S.C.ALMOTITL CRYSTAL STRUCTURE OF HUMAN B7-H4 IGV-LIKE DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2vgq MAVS crystal structure of human ips-1 card 2.1Å AUTH J.A.POTTER,R.E.RANDALL,G.L.TAYLORTITL CRYSTAL STRUCTURE OF HUMAN IPS-1 CASPASETITL 2 ACTIVATION RECRUITMENT DOMAINREF BMC STRUCT.BIOL. V. 8 11 2008REFN ISSN 1472-6807PMID 18307765DOI 10.1186/1472-6807-8-11 Variant Set Distributions Mapped Variants