Assessment of Structural Intolerance and Durability
General Structure Information 2m1w TICAM2 ticam-2 tir domain -1.0Å AUTH Y.ENOKIZONO,H.KUMETA,K.FUNAMI,M.HORIUCHI,J.SARMIENTO,AUTH 2 K.YAMASHITA,D.M.STANDLEY,M.MATSUMOTO,T.SEYA,F.INAGAKITITL STRUCTURES AND INTERFACE MAPPING OF THE TIRTITL 2 DOMAIN-CONTAINING ADAPTOR MOLECULES INVOLVED IN INTERFERONTITL 3 SIGNALING.REF PROC.NATL.ACAD.SCI.USA V. 110 19908 2013REFN ISSN 0027-8424PMID 24255114DOI 10.1073/PNAS.1222811110 Variant Set Distributions Mapped Variants
General Structure Information 2dyp LILRB2 crystal structure of lilrb2(lir2/ilt4/cd85d) complexed with hla-g 2.5Å AUTH M.SHIROISHI,K.KUROKI,L.RASUBALA,K.TSUMOTO,AUTH 2 I.KUMAGAI,E.KURIMOTO,K.KATO,D.KOHDA,K.MAENAKATITL STRUCTURAL BASIS FOR RECOGNITION OF THETITL 2 NONCLASSICAL MHC MOLECULE HLA-G BY THE LEUKOCYTETITL 3 IG-LIKE RECEPTOR B2 (LILRB2/LIR2/ILT4/CD85D)REF PROC.NATL.ACAD.SCI.USA V. 103 16412 2006REFN ISSN 0027-8424PMID 17056715DOI 10.1073/PNAS.0605228103 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 2ypa LDB1 structure of the scl:e47:lmo2:ldb1 complex bound to dna 2.8Å AUTH K.EL OMARI,S.J.HOOSDALLY,K.TULADHAR,D.KARIA,E.HALL-PONSELE,AUTH 2 O.PLATONOVA,P.VYAS,R.PATIENT,C.PORCHER,E.J.MANCINITITL STRUCTURAL BASIS FOR LMO2-DRIVEN RECRUITMENT OF THETITL 2 SCL:E47BHLH HETERODIMER TO HEMATOPOIETIC-SPECIFICTITL 3 TRANSCRIPTIONAL TARGETS.REF CELL REP. V. 4 135 2013REFN ISSN 2211-1247PMID 23831025DOI 10.1016/J.CELREP.2013.06.008 Variant Set Distributions Mapped Variants
General Structure Information 2m5v NLRP10 three-dimensional structure of human nlrp10/pynod pyrin domain -1.0Å AUTH M.Y.SU,C.I.KUO,C.F.CHANG,C.I.CHANGTITL THREE-DIMENSIONAL STRUCTURE OF HUMAN NLRP10/PYNOD PYRINTITL 2 DOMAIN REVEALS A HOMOTYPIC INTERACTION SITE DISTINCT FROMTITL 3 ITS MOUSE HOMOLOGUE.REF PLOS ONE V. 8 67843 2013REFN ESSN 1932-6203PMID 23861819DOI 10.1371/JOURNAL.PONE.0067843 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 3p2t LILRB4 crystal structure of leukocyte ig-like receptor lilrb4 (ilt3/lir- 5/cd85k) 1.7Å AUTH H.CHENG,F.MOHAMMED,G.NAM,Y.CHEN,J.QI,L.I.GARNER,R.L.ALLEN,AUTH 2 J.YAN,B.E.WILLCOX,G.F.GAOTITL CRYSTAL STRUCTURE OF LEUKOCYTE IG-LIKE RECEPTOR LILRB4TITL 2 (ILT3/LIR-5/CD85K): A MYELOID INHIBITORY RECEPTOR INVOLVEDTITL 3 IN IMMUNE TOLERANCEREF J.BIOL.CHEM. V. 286 18013 2011REFN ISSN 0021-9258PMID 21454581DOI 10.1074/JBC.M111.221028 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 4lla LILRB2 crystal structure of d3d4 domain of the lilrb2 molecule 2.5Å AUTH G.NAM,Y.SHI,M.RYU,Q.WANG,H.SONG,J.LIU,J.YAN,J.QI,G.F.GAOTITL CRYSTAL STRUCTURES OF THE TWO MEMBRANE-PROXIMAL IG-LIKETITL 2 DOMAINS (D3D4) OF LILRB1/B2: ALTERNATIVE MODELS FOR THEIRTITL 3 INVOLVEMENT IN PEPTIDE-HLA BINDINGREF PROTEIN CELL V. 4 761 2013REFN ISSN 1674-800XPMID 23955630DOI 10.1007/S13238-013-3908-X Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 4ll9 LILRB1 crystal structure of d3d4 domain of the lilrb1 molecule 2.69Å AUTH G.NAM,Y.SHI,M.RYU,Q.WANG,H.SONG,J.LIU,J.YAN,J.QI,G.F.GAOTITL CRYSTAL STRUCTURES OF THE TWO MEMBRANE-PROXIMAL IG-LIKETITL 2 DOMAINS (D3D4) OF LILRB1/B2: ALTERNATIVE MODELS FOR THEIRTITL 3 INVOLVEMENT IN PEPTIDE-HLA BINDINGREF PROTEIN CELL V. 4 761 2013REFN ISSN 1674-800XPMID 23955630DOI 10.1007/S13238-013-3908-X Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 1ugn LILRB1 crystal structure of lir1.02, one of the alleles of lir1 1.8Å AUTH K.KUROKI,N.TSUCHIYA,M.SHIROISHI,L.RASUBALA,AUTH 2 Y.YAMASHITA,K.MATSUTA,T.FUKAZAWA,M.KUSAOI,AUTH 3 Y.MURAKAMI,M.TAKIGUCHI,T.JUJI,H.HASHIMOTO,D.KOHDA,AUTH 4 K.MAENAKA,K.TOKUNAGATITL EXTENSIVE POLYMORPHISMS OF LILRB1 (ILT2, LIR1) ANDTITL 2 THEIR ASSOCIATION WITH HLA-DRB1 SHARED EPITOPETITL 3 NEGATIVE RHEUMATOID ARTHRITIS.REF HUM.MOL.GENET. V. 14 2469 2005REFN ISSN 0964-6906PMID 16014635DOI 10.1093/HMG/DDI247 Variant Set Distributions Ripley’s […]
General Structure Information 3of6 PTCRA human pre-t cell receptor crystal structure 2.8Å AUTH S.S.PANG,R.BERRY,Z.CHEN,L.KJER-NIELSEN,M.A.PERUGINI,AUTH 2 G.F.KING,C.WANG,S.H.CHEW,N.L.LA GRUTA,N.K.WILLIAMS,T.BEDDOE,AUTH 3 T.TIGANIS,N.P.COWIESON,D.I.GODFREY,A.W.PURCELL,M.C.J.WILCE,AUTH 4 J.MCCLUSKEY,J.ROSSJOHNTITL THE STRUCTURAL BASIS FOR AUTONOMOUS DIMERIZATION OF THETITL 2 PRE-T-CELL ANTIGEN RECEPTORREF NATURE V. 467 844 2010REFN ISSN 0028-0836PMID 20944746DOI 10.1038/NATURE09448 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3f4m TNFAIP8L2 crystal structure of tipe2 1.7Å AUTH X.ZHANG,J.WANG,C.FAN,H.LI,H.SUN,S.GONG,Y.H.CHEN,AUTH 2 Y.SHITITL CRYSTAL STRUCTURE OF TIPE2 PROVIDES INSIGHTS INTOTITL 2 IMMUNE HOMEOSTASISREF NAT.STRUCT.MOL.BIOL. V. 16 89 2009REFN ISSN 1545-9993PMID 19079267DOI 10.1038/NSMB.1522 Variant Set Distributions Mapped Variants