General Structure Information
| PDB ID | 1ugn |
| HGNC Gene Label(s) | LILRB1 |
| Structure Name | crystal structure of lir1.02, one of the alleles of lir1 |
| Resolution | 1.8Å |
| Reference | AUTH K.KUROKI,N.TSUCHIYA,M.SHIROISHI,L.RASUBALA,AUTH 2 Y.YAMASHITA,K.MATSUTA,T.FUKAZAWA,M.KUSAOI,AUTH 3 Y.MURAKAMI,M.TAKIGUCHI,T.JUJI,H.HASHIMOTO,D.KOHDA,AUTH 4 K.MAENAKA,K.TOKUNAGATITL EXTENSIVE POLYMORPHISMS OF LILRB1 (ILT2, LIR1) ANDTITL 2 THEIR ASSOCIATION WITH HLA-DRB1 SHARED EPITOPETITL 3 NEGATIVE RHEUMATOID ARTHRITIS.REF HUM.MOL.GENET. V. 14 2469 2005REFN ISSN 0964-6906PMID 16014635DOI 10.1093/HMG/DDI247 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 186 |
| Number Of SNVs | 61 |
| Number Of Permutations | 26184 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.062 |
| p-value | 0.979 |
COSMIC
| Number Of Residues | 186 |
| Number Of SNVs | 11 |
| Number Of Permutations | 6859 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.582 |
| p-value | 0.143 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 61 |
| Number Of COSMIC SNVs | 10 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.112 |
| p-value | 0.132 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
