General Structure Information 3v6o LEPR leptin receptor-antibody complex 1.95Å AUTH B.CARPENTER,G.R.HEMSWORTH,Z.WU,M.MAAMRA,C.J.STRASBURGER,AUTH 2 R.J.ROSS,P.J.ARTYMIUKTITL STRUCTURE OF THE HUMAN OBESITY RECEPTOR LEPTIN-BINDINGTITL 2 DOMAIN REVEALS THE MECHANISM OF LEPTIN ANTAGONISM BY ATITL 3 MONOCLONAL ANTIBODY.REF STRUCTURE V. 20 487 2012REFN ISSN 0969-2126PMID 22405007DOI 10.1016/J.STR.2012.01.019 Variant Set Distributions Mapped Variants
General Structure Information 2g2b AIF1 nmr structure of the human allograft inflammatory factor 1 -1.0Å AUTH J.SONG,R.C.TYLER,C.L.NEWMAN,D.VINAROV,J.L.MARKLEYTITL NMR STRUCTURE OF THE HUMAN ALLOGRAFT INFLAMMATORYTITL 2 FACTOR 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1i8l CD80 human b7-1/ctla-4 co-stimulatory complex 3.0Å AUTH C.C.STAMPER,Y.ZHANG,J.F.TOBIN,D.V.ERBE,S.IKEMIZU,S.J.DAVIS,AUTH 2 M.L.STAHL,J.SEEHRA,W.S.SOMERS,L.MOSYAKTITL CRYSTAL STRUCTURE OF THE B7-1/CTLA-4 COMPLEX THAT INHIBITSTITL 2 HUMAN IMMUNE RESPONSES.REF NATURE V. 410 608 2001REFN ISSN 0028-0836PMID 11279502DOI 10.1038/35069118 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2×57 VIPR2 crystal structure of the extracellular domain of human vasoactive intestinal polypeptide receptor 2 2.1Å AUTH A.C.W.PIKE,A.J.BARR,A.QUIGLEY,N.BURGESS BROWN,A.DE RISO,AUTH 2 A.BULLOCK,G.BERRIDGE,J.R.C.MUNIZ,A.CHAIKAUD,M.VOLLMAR,AUTH 3 T.KROJER,E.UGOCHUKWU,F.VON DELFT,A.EDWARDS,C.H.ARROWSMITH,AUTH 4 J.WEIGELT,C.BOUNTRA,E.P.CARPENTERTITL CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMANTITL 2 VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3zd1 CFHR2 structure of the two c-terminal domains of complement factor h related protein 2 2.0Å AUTH E.GOICOECHEA DE JORGE,J.J.E.CAESAR,T.H.MALIK,M.PATEL,AUTH 2 M.COLLEDGE,S.JOHNSON,S.HAKOBYAN,B.P.MORGAN,C.L.HARRIS,AUTH 3 M.C.PICKERING,S.M.LEATITL DIMERIZATION OF COMPLEMENT FACTOR H-RELATED PROTEINSTITL 2 MODULATES COMPLEMENT ACTIVATION IN VIVO.REF PROC.NATL.ACAD.SCI.USA V. 110 4685 2013REFN ISSN 0027-8424PMID 23487775DOI 10.1073/PNAS.1219260110 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 1t0p ICAM3 structural basis of icam recognition by integrin alpahlbeta2 revealed in the complex structure of binding domains of icam-3 and alphalbeta2 at 1.65 a 1.66Å AUTH G.SONG,Y.YANG,J.H.LIU,J.M.CASASNOVAS,M.SHIMAOKA,AUTH 2 T.A.SPRINGER,J.H.WANGTITL AN ATOMIC RESOLUTION VIEW OF ICAM RECOGNITION IN A COMPLEXTITL 2 BETWEEN THE BINDING DOMAINS OF ICAM-3 AND INTEGRINTITL 3 ALPHALBETA2.REF PROC.NATL.ACAD.SCI.USA […]
General Structure Information 3l5w IL13 crystal structure of the complex between il-13 and c836 fab 2.0Å AUTH J.FRANSSON,A.TEPLYAKOV,G.RAGHUNATHAN,E.CHI,W.CORDIER,AUTH 2 T.DINH,Y.FENG,J.GILES-KOMAR,G.GILLILAND,B.LOLLO,T.J.MALIA,AUTH 3 W.NISHIOKA,G.OBMOLOVA,S.ZHAO,Y.ZHAO,R.V.SWANSON,J.C.ALMAGROTITL HUMAN FRAMEWORK ADAPTATION OF A MOUSE ANTI-HUMAN IL-13TITL 2 ANTIBODY.REF J.MOL.BIOL. V. 398 214 2010REFN ISSN 0022-2836PMID 20226193DOI 10.1016/J.JMB.2010.03.004 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 2fcb FCGR2B human fc gamma receptor iib ectodomain (cd32) 1.74Å AUTH P.SONDERMANN,R.HUBER,U.JACOBTITL CRYSTAL STRUCTURE OF THE SOLUBLE FORM OF THE HUMANTITL 2 FCGAMMA-RECEPTOR IIB: A NEW MEMBER OF THETITL 3 IMMUNOGLOBULIN SUPERFAMILY AT 1.7 A RESOLUTION.REF EMBO J. V. 18 1095 1999REFN ISSN 0261-4189PMID 10064577DOI 10.1093/EMBOJ/18.5.1095 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 2wa0 MAGEA4 crystal structure of the human magea4 2.3Å AUTH A.K.ROOS,C.D.O.COOPER,E.UGOCHUKWU,W.W YUE,G.BERRIDGE,AUTH 2 J.M.ELKINS,A.C.W.PIKE,J.BRAY,P.FILIPPAKOPOULOS,J.MUNIZ,AUTH 3 A.CHAIKUAD,N.BURGESS-BROWN,C.H.ARROWSMITH,J.WEIGELT,AUTH 4 A.EDWARDS,C.BOUNTRA,F.VON DELFT,O.GILEADI,U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE HUMAN MAGEA4AREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1ncn CD86 the receptor-binding domain of human b7-2 2.7Å AUTH X.ZHANG,J.D.SCHWARTZ,S.C.ALMO,S.G.NATHENSONTITL CRYSTAL STRUCTURE OF THE RECEPTOR-BINDING DOMAINTITL 2 OF HUMAN B7-2: INSIGHTS INTO ORGANIZATION ANDTITL 3 SIGNALINGREF PROC.NATL.ACAD.SCI.USA V. 100 2586 2003REFN ISSN 0027-8424PMID 12606712DOI 10.1073/PNAS.252771499 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants