General Structure Information
| PDB ID | 3zd1 |
| HGNC Gene Label(s) | CFHR2 |
| Structure Name | structure of the two c-terminal domains of complement factor h related protein 2 |
| Resolution | 2.0Å |
| Reference | AUTH E.GOICOECHEA DE JORGE,J.J.E.CAESAR,T.H.MALIK,M.PATEL,AUTH 2 M.COLLEDGE,S.JOHNSON,S.HAKOBYAN,B.P.MORGAN,C.L.HARRIS,AUTH 3 M.C.PICKERING,S.M.LEATITL DIMERIZATION OF COMPLEMENT FACTOR H-RELATED PROTEINSTITL 2 MODULATES COMPLEMENT ACTIVATION IN VIVO.REF PROC.NATL.ACAD.SCI.USA V. 110 4685 2013REFN ISSN 0027-8424PMID 23487775DOI 10.1073/PNAS.1219260110 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 123 |
| Number Of SNVs | 35 |
| Number Of Permutations | 16223 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.113 |
| p-value | 0.676 |
COSMIC
| Number Of Residues | 123 |
| Number Of SNVs | 3 |
| Number Of Permutations | 277 |
| Optimal Distance Threshold | 28.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
