Assessment of Structural Intolerance and Durability
General Structure Information 3ch4 PMVK the crystal structure of human phosphomavelonate kinase at 1.8 a resolution 1.76Å AUTH Q.CHANG,X.-X.YAN,S.-Y.GU,J.-F.LIU,D.-C.LIANGTITL CRYSTAL STRUCTURE OF HUMAN PHOSPHOMAVELONATETITL 2 KINASE AT 1.8 A RESOLUTIONREF PROTEINS V. 73 254 2008REFN ISSN 0887-3585PMID 18618710DOI 10.1002/PROT.22151 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2r3v MVK the biochemical and structural basis for feedback inhibition of mevalonate kinase and isoprenoid metabolism 2.5Å AUTH Z.FU,N.E.VOYNOVA,T.J.HERDENDORF,H.M.MIZIORKO,AUTH 2 J.J.KIMTITL BIOCHEMICAL AND STRUCTURAL BASIS FOR FEEDBACKTITL 2 INHIBITION OF MEVALONATE KINASE AND ISOPRENOIDTITL 3 METABOLISM.REF BIOCHEMISTRY V. 47 3715 2008REFN ISSN 0006-2960PMID 18302342DOI 10.1021/BI7024386 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2r3v MVK the biochemical and structural basis for feedback inhibition of mevalonate kinase and isoprenoid metabolism 2.5Å AUTH Z.FU,N.E.VOYNOVA,T.J.HERDENDORF,H.M.MIZIORKO,AUTH 2 J.J.KIMTITL BIOCHEMICAL AND STRUCTURAL BASIS FOR FEEDBACKTITL 2 INHIBITION OF MEVALONATE KINASE AND ISOPRENOIDTITL 3 METABOLISM.REF BIOCHEMISTRY V. 47 3715 2008REFN ISSN 0006-2960PMID 18302342DOI 10.1021/BI7024386 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2r3v MVK the biochemical and structural basis for feedback inhibition of mevalonate kinase and isoprenoid metabolism 2.5Å AUTH Z.FU,N.E.VOYNOVA,T.J.HERDENDORF,H.M.MIZIORKO,AUTH 2 J.J.KIMTITL BIOCHEMICAL AND STRUCTURAL BASIS FOR FEEDBACKTITL 2 INHIBITION OF MEVALONATE KINASE AND ISOPRENOIDTITL 3 METABOLISM.REF BIOCHEMISTRY V. 47 3715 2008REFN ISSN 0006-2960PMID 18302342DOI 10.1021/BI7024386 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2eap LCP2 solution structure of the n-terminal sam-domain of human lymphocyte cytosolic protein 2 -1.0Å AUTH A.K.GORONCY,M.SATO,N.TOCHIO,S.KOSHIBA,S.WATANABE,AUTH 2 T.HARADA,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE N-TERMINAL SAM-DOMAIN OFTITL 2 HUMAN LYMPHOCYTE CYTOSOLIC PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ytu FLI1 solution structure of the sam_pnt-domain of the human friend leukemiaintegration 1 transcription factor -1.0Å AUTH A.K.GORONCY,M.SATO,N.TOCHIO,S.KOSHIBA,S.WATANABE,AUTH 2 T.HARADA,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SAM_PNT-DOMAIN OF THETITL 2 HUMAN FRIEND LEUKEMIAINTEGRATION 1 TRANSCRIPTIONTITL 3 FACTORREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2e8p ELF3 solution structure of the n-terminal sam-domain of e74-like factor 3 -1.0Å AUTH A.K.GORONCY,M.SATO,S.KOSHIBA,S.WATANABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE N-TERMINAL SAM-DOMAIN OFTITL 2 E74-LIKE FACTOR 3REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4j6s YWHAG 14-3-3gamma complexed with the n-terminal sequence of tyrosine hydroxylase (residues 1-43) 3.08Å AUTH A.A.SKJEVIK,M.MILENI,A.BAUMANN,O.HALSKAU,K.TEIGEN,AUTH 2 R.C.STEVENS,A.MARTINEZTITL THE N-TERMINAL SEQUENCE OF TYROSINE HYDROXYLASE IS ATITL 2 CONFORMATIONALLY VERSATILE MOTIF THAT BINDS 14-3-3 PROTEINSTITL 3 AND MEMBRANES.REF J.MOL.BIOL. V. 426 150 2014REFN ISSN 0022-2836PMID 24055376DOI 10.1016/J.JMB.2013.09.012 Variant Set Distributions Mapped Variants
General Structure Information 2ytu FLI1 solution structure of the sam_pnt-domain of the human friend leukemiaintegration 1 transcription factor -1.0Å AUTH A.K.GORONCY,M.SATO,N.TOCHIO,S.KOSHIBA,S.WATANABE,AUTH 2 T.HARADA,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SAM_PNT-DOMAIN OF THETITL 2 HUMAN FRIEND LEUKEMIAINTEGRATION 1 TRANSCRIPTIONTITL 3 FACTORREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2e8p ELF3 solution structure of the n-terminal sam-domain of e74-like factor 3 -1.0Å AUTH A.K.GORONCY,M.SATO,S.KOSHIBA,S.WATANABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE N-TERMINAL SAM-DOMAIN OFTITL 2 E74-LIKE FACTOR 3REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants