Assessment of Structural Intolerance and Durability
General Structure Information 4dl3 POLH human dna polymerase eta inserting dcmpnpp opposite gg template (gg0b). 2.1Å AUTH Y.ZHAO,C.BIERTUMPFEL,M.T.GREGORY,Y.J.HUA,F.HANAOKA,W.YANGTITL STRUCTURAL BASIS FOR CHEMORESISTANCE TO CISPLATIN MEDIATEDTITL 2 BY DNA POLYMERASE ETAREF PROC.NATL.ACAD.SCI.USA V. 109 7269 2012REFN ISSN 0027-8424PMID 22529383DOI 10.1073/PNAS.1202681109 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3abd MAD2L2 structure of human rev7 in complex with a human rev3 fragment in a monoclinic crystal 1.9Å AUTH K.HARA,H.HASHIMOTO,Y.MURAKUMO,S.KOBAYASHI,T.KOGAME,S.UNZAI,AUTH 2 S.AKASHI,S.TAKEDA,T.SHIMIZU,M.SATOTITL CRYSTAL STRUCTURE OF HUMAN REV7 IN COMPLEX WITH A HUMAN REV3TITL 2 FRAGMENT AND STRUCTURAL IMPLICATION OF THE INTERACTIONTITL 3 BETWEEN DNA POLYMERASE {ZETA} AND REV1REF J.BIOL.CHEM. V. 285 12299 […]
General Structure Information 3gqc REV1 structure of human rev1-dna-dntp ternary complex 2.5Å AUTH M.K.SWAN,R.E.JOHNSON,L.PRAKASH,S.PRAKASH,A.K.AGGARWALTITL STRUCTURE OF THE HUMAN REV1-DNA-DNTP TERNARY COMPLEX.REF J.MOL.BIOL. V. 390 699 2009REFN ISSN 0022-2836PMID 19464298DOI 10.1016/J.JMB.2009.05.026 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1×67 DBNL solution structure of the cofilin homology domain of hip-55 (drebrin-like protein) -1.0Å AUTH A.K.GORONCY,S.KOSHIBA,N.TOCHIO,T.TOMIZAWA,M.SATO,AUTH 2 M.INOUE,S.WATANABE,Y.HAYASHIZAKI,A.TANAKA,T.KIGAWA,AUTH 3 S.YOKOYAMATITL NMR SOLUTION STRUCTURES OF ACTIN DEPOLYMERIZINGTITL 2 FACTOR HOMOLOGY DOMAINS.REF PROTEIN SCI. V. 18 2384 2009REFN ISSN 0961-8368PMID 19768801DOI 10.1002/PRO.248 Variant Set Distributions Mapped Variants
General Structure Information 3gv7 POLI human dna polymerase iota in complex with t template dna and incoming dttp 2.2Å AUTH K.N.KIROUAC,H.LINGTITL STRUCTURAL BASIS OF ERROR-PRONE REPLICATION AND STALLING ATTITL 2 A THYMINE BASE BY HUMAN DNA POLYMERASE IOTAREF EMBO J. V. 28 1644 2009REFN ISSN 0261-4189PMID 19440206DOI 10.1038/EMBOJ.2009.122 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3in5 POLK structure of human dna polymerase kappa inserting datp opposite an 8-oxog dna lesion 3.2Å AUTH R.VASQUEZ-DEL CARPIO,T.D.SILVERSTEIN,S.LONE,AUTH 2 M.K.SWAN,J.R.CHOUDHURY,R.E.JOHNSON,S.PRAKASH,AUTH 3 L.PRAKASH,A.K.AGGARWALTITL STRUCTURE OF HUMAN DNA POLYMERASE KAPPA INSERTINGTITL 2 DATP OPPOSITE AN 8-OXOG DNA LESIONREF PLOS ONE V. 4 E5766 2009REFN ESSN 1932-6203PMID 19492058DOI 10.1371/JOURNAL.PONE.0005766 Variant Set Distributions Pathogenic Proximity […]
General Structure Information 2ebw REV1 solution structure of the brct domain from human dna repair protein rev1 -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE BRCT DOMAIN FROM HUMANTITL 2 DNA REPAIR PROTEIN REV1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2l0f POLI solution nmr structure of human polymerase iota ubm2 (p692a mutant) in complex with ubiquitin -1.0Å AUTH G.CUI,R.C.BENIRSCHKE,H.F.TUAN,N.JURANIC,S.MACURA,AUTH 2 M.V.BOTUYAN,G.MERTITL STRUCTURAL BASIS OF UBIQUITIN RECOGNITION BY TRANSLESIONTITL 2 SYNTHESIS DNA POLYMERASE IOTA.REF BIOCHEMISTRY V. 49 10198 2010REFN ISSN 0006-2960PMID 21049971DOI 10.1021/BI101303T Variant Set Distributions Mapped Variants
General Structure Information 2jw5 POLL polymerase lambda brct domain -1.0Å AUTH G.A.MUELLER,A.F.MOON,E.F.DEROSE,B.J.DAVIS,AUTH 2 D.A.RAMSDEN,L.C.PEDERSEN,R.E.LONDONTITL POLYMERASE LAMBDA BRCT DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2iwz OXSM human mitochondrial beta-ketoacyl acp synthase complexed with hexanoic acid 1.65Å AUTH C.E.CHRISTENSEN,B.B.KRAGELUND,P.VON WETTSTEIN-KNOWLES,AUTH 2 A.HENRIKSENTITL STRUCTURE OF THE HUMAN BETA-KETOACYL [ACP] SYNTHASE FROMTITL 2 THE MITOCHONDRIAL TYPE II FATTY ACID SYNTHASE.REF PROTEIN SCI. V. 16 261 2007REFN ISSN 0961-8368PMID 17242430DOI 10.1110/PS.062473707 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]