General Structure Information
| PDB ID | 3ch4 |
| HGNC Gene Label(s) | PMVK |
| Structure Name | the crystal structure of human phosphomavelonate kinase at 1.8 a resolution |
| Resolution | 1.76Å |
| Reference | AUTH Q.CHANG,X.-X.YAN,S.-Y.GU,J.-F.LIU,D.-C.LIANGTITL CRYSTAL STRUCTURE OF HUMAN PHOSPHOMAVELONATETITL 2 KINASE AT 1.8 A RESOLUTIONREF PROTEINS V. 73 254 2008REFN ISSN 0887-3585PMID 18618710DOI 10.1002/PROT.22151 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 185 |
| Number Of SNVs | 45 |
| Number Of Permutations | 4273 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.153 |
| p-value | 0.666 |
COSMIC
| Number Of Residues | 185 |
| Number Of SNVs | 3 |
| Number Of Permutations | 27 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 45 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | -0.286 |
| p-value | 0.794 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
