Assessment of Structural Intolerance and Durability
General Structure Information 2cub NCK1 solution structure of the sh3 domain of the human cytoplasmic protein nck1 -1.0Å AUTH S.OHNISHI,T.KIGAWA,M.SATO,T.TOMIZAWA,S.KOSHIBA,AUTH 2 M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN OF THE HUMANTITL 2 CYTOPLASMIC PROTEIN NCK1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2b0u FST the structure of the follistatin:activin complex 2.8Å AUTH T.B.THOMPSON,T.F.LERCH,R.W.COOK,T.K.WOODRUFF,T.S.JARDETZKYTITL THE STRUCTURE OF THE FOLLISTATIN:ACTIVIN COMPLEX REVEALSTITL 2 ANTAGONISM OF BOTH TYPE I AND TYPE II RECEPTOR BINDING.REF DEV.CELL V. 9 535 2005REFN ISSN 1534-5807PMID 16198295DOI 10.1016/J.DEVCEL.2005.09.008 Variant Set Distributions Mapped Variants
General Structure Information 2w2v RAC2 rac2 (g12v) in complex with gtpgs 2.0Å AUTH T.D.BUNNEY,O.OPALEYE,S.M.ROE,P.VATTER,AUTH 2 R.W.BAXENDALE,C.WALLISER,K.L.EVERETT,M.B.JOSEPHS,AUTH 3 C.CHRISTOW,F.RODRIGUES-LIMA,P.GIERSCHIK,L.H.PEARL,AUTH 4 M.KATANTITL STRUCTURAL INSIGHTS INTO FORMATION OF AN ACTIVETITL 2 SIGNALING COMPLEX BETWEEN RAC AND PHOSPHOLIPASE CTITL 3 GAMMA 2.REF MOL.CELL V. 34 223 2009REFN ISSN 1097-2765PMID 19394299DOI 10.1016/J.MOLCEL.2009.02.023 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 2qcq BMP3 crystal structure of bone morphogenetic protein-3 (bmp-3) 2.21Å AUTH G.P.ALLENDORPH,M.J.ISAACS,Y.KAWAKAMI,J.C.BELMONTE,S.CHOETITL BMP-3 AND BMP-6 STRUCTURES ILLUMINATE THE NATURE OF BINDINGTITL 2 SPECIFICITY WITH RECEPTORS.REF BIOCHEMISTRY V. 46 12238 2007REFN ISSN 0006-2960PMID 17924656DOI 10.1021/BI700907K Variant Set Distributions Mapped Variants
General Structure Information 2ror VAV1 solution structure of the vav1 sh2 domain complexed with a tyrosine-phosphorylated peptide from slp76 -1.0Å AUTH T.KASAI,M.TANAKA,S.KOSHIBA,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE VAV1 SH2 DOMAINTITL 2 COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDETITL 3 FROM SLP76REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dbf NFKB1 solution structure of the death domain in human nuclear factor nf-kappa-b p105 subunit -1.0Å AUTH K.SAITO,M.INOUE,S.KOSHIBA,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE DEATH DOMAIN IN HUMANTITL 2 NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNITREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1e96 NCF2 structure of the rac/p67phox complex 2.4Å AUTH K.LAPOUGE,S.J.M.SMTIH,P.A.WALKER,S.J.GAMBLIN,AUTH 2 S.J.SMERDON,K.RITTINGERTITL STRUCTURE OF THE TPR DOMAIN OF P67PHOX IN COMPLEXTITL 2 WITH RAC.GTPREF MOL.CELL V. 6 899 2000REFN ISSN 1097-2765PMID 11090627 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1dv8 ASGR1 crystal structure of the carbohydrate recognition domain of the h1 subunit of the asialoglycoprotein receptor 2.3Å AUTH M.MEIER,M.D.BIDER,V.N.MALASHKEVICH,M.SPIESS,AUTH 2 P.BURKHARDTITL CRYSTAL STRUCTURE OF THE CARBOHYDRATE RECOGNITIONTITL 2 DOMAIN OF THE H1 SUBUNIT OF THE ASIALOGLYCOPROTEINTITL 3 RECEPTOR.REF J.MOL.BIOL. V. 300 857 2000REFN ISSN 0022-2836PMID 10891274DOI 10.1006/JMBI.2000.3853 Variant Set Distributions Mapped […]
General Structure Information 2uzx MET structure of the human receptor tyrosine kinase met in complex with the listeria monocytogenes invasion protein inlb: crystal form i 2.8Å AUTH H.H.NIEMANN,V.JAGER,P.J.G.BUTLER,J.VAN DEN HEUVEL,AUTH 2 S.SCHMIDT,D.FERRARIS,E.GHERARDI,D.W.HEINZTITL STRUCTURE OF THE HUMAN RECEPTOR TYROSINE KINASETITL 2 MET IN COMPLEX WITH THE LISTERIA INVASION PROTEINTITL 3 INLBREF CELL(CAMBRIDGE,MASS.) V. 130 235 2007REFN […]
General Structure Information 1k9k S100A6 crystal structure of calcium bound human s100a6 1.76Å AUTH L.R.OTTERBEIN,J.KORDOWSKA,C.WITTE-HOFFMANN,AUTH 2 C.L.WANG,R.DOMINGUEZTITL CRYSTAL STRUCTURES OF S100A6 IN THE CA(2+)-FREETITL 2 AND CA(2+)-BOUND STATES: THE CALCIUM SENSORTITL 3 MECHANISM OF S100 PROTEINS REVEALED AT ATOMICTITL 4 RESOLUTION.REF STRUCTURE V. 10 557 2002REFN ISSN 0969-2126PMID 11937060DOI 10.1016/S0969-2126(02)00740-2 Variant Set Distributions Mapped Variants