Assessment of Structural Intolerance and Durability
General Structure Information 3F5N SERPINI1 structure of native human neuroserpin 3.15Å AUTH S.RICAGNO,S.CACCIA,G.SORRENTINO,G.ANTONINI,M.BOLOGNESITITL HUMAN NEUROSERPIN: STRUCTURE AND TIME-DEPENDENT INHIBITIONREF J.MOL.BIOL. V. 388 109 2009REFN ISSN 0022-2836PMID 19265707DOI 10.1016/J.JMB.2009.02.056 Variant Set Distributions Ripley’s K Analysis Plots
General Structure Information 3F5N SERPINI1 structure of native human neuroserpin 3.15Å AUTH S.RICAGNO,S.CACCIA,G.SORRENTINO,G.ANTONINI,M.BOLOGNESITITL HUMAN NEUROSERPIN: STRUCTURE AND TIME-DEPENDENT INHIBITIONREF J.MOL.BIOL. V. 388 109 2009REFN ISSN 0022-2836PMID 19265707DOI 10.1016/J.JMB.2009.02.056 Variant Set Distributions Ripley’s K Analysis Plots
General Structure Information 3F5N SERPINI1 structure of native human neuroserpin 3.15Å AUTH S.RICAGNO,S.CACCIA,G.SORRENTINO,G.ANTONINI,M.BOLOGNESITITL HUMAN NEUROSERPIN: STRUCTURE AND TIME-DEPENDENT INHIBITIONREF J.MOL.BIOL. V. 388 109 2009REFN ISSN 0022-2836PMID 19265707DOI 10.1016/J.JMB.2009.02.056 Variant Set Distributions Ripley’s K Analysis Plots
General Structure Information 3F5N SERPINI1 structure of native human neuroserpin 3.15Å AUTH S.RICAGNO,S.CACCIA,G.SORRENTINO,G.ANTONINI,M.BOLOGNESITITL HUMAN NEUROSERPIN: STRUCTURE AND TIME-DEPENDENT INHIBITIONREF J.MOL.BIOL. V. 388 109 2009REFN ISSN 0022-2836PMID 19265707DOI 10.1016/J.JMB.2009.02.056 Variant Set Distributions Ripley’s K Analysis Plots
General Structure Information 3f5n SERPINI1 structure of native human neuroserpin 3.15Å AUTH S.RICAGNO,S.CACCIA,G.SORRENTINO,G.ANTONINI,M.BOLOGNESITITL HUMAN NEUROSERPIN: STRUCTURE AND TIME-DEPENDENT INHIBITIONREF J.MOL.BIOL. V. 388 109 2009REFN ISSN 0022-2836PMID 19265707DOI 10.1016/J.JMB.2009.02.056 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4if8 SERPINA12 structure of vaspin 2.08Å AUTH J.T.HEIKER,N.KLOTING,P.KOVACS,E.B.KUETTNER,N.STRATER,AUTH 2 S.SCHULTZ,M.KERN,M.STUMVOLL,M.BLUHER,A.G.BECK-SICKINGERTITL VASPIN INHIBITS KALLIKREIN 7 BY SERPIN MECHANISMREF CELL.MOL.LIFE SCI. V. 70 2569 2013REFN ISSN 1420-682XPMID 23370777DOI 10.1007/S00018-013-1258-8 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4ga7 SERPINB1 crystal structure of human serpinb1 mutant 2.9Å AUTH L.WANG,Q.LI,L.WU,S.LIU,Y.ZHANG,X.YANG,P.ZHU,H.ZHANG,K.ZHANG,AUTH 2 J.LOU,P.LIU,L.TONG,F.SUN,Z.FANTITL IDENTIFICATION OF SERPINB1 AS A PHYSIOLOGICAL INHIBITOR OFTITL 2 HUMAN GRANZYME HREF J.IMMUNOL. V. 190 1319 2013REFN ISSN 0022-1767PMID 23269243DOI 10.4049/JIMMUNOL.1202542 Variant Set Distributions Mapped Variants
General Structure Information 1wz9 SERPINB5 the 2.1 a structure of a tumour suppressing serpin 2.1Å AUTH R.H.LAW,J.A.IRVING,A.M.BUCKLE,K.RUZYLA,M.BUZZA,AUTH 2 T.A.BASHTANNYK-PUHALOVICH,T.C.BEDDOE,K.NGUYEN,AUTH 3 D.M.WORRALL,S.P.BOTTOMLEY,P.I.BIRD,J.ROSSJOHN,AUTH 4 J.C.WHISSTOCKTITL THE HIGH RESOLUTION CRYSTAL STRUCTURE OF THE HUMANTITL 2 TUMOR SUPPRESSOR MASPIN REVEALS A NOVELTITL 3 CONFORMATIONAL SWITCH IN THE G-HELIX.REF J.BIOL.CHEM. V. 280 22356 2005REFN ISSN 0021-9258PMID 15760906DOI 10.1074/JBC.M412043200 Variant Set […]
General Structure Information 1imv SERPINF1 2.85 a crystal structure of pedf 2.85Å AUTH M.SIMONOVIC,P.G.GETTINS,K.VOLZTITL CRYSTAL STRUCTURE OF HUMAN PEDF, A POTENT ANTI-ANGIOGENICTITL 2 AND NEURITE GROWTH-PROMOTING FACTOR.REF PROC.NATL.ACAD.SCI.USA V. 98 11131 2001REFN ISSN 0027-8424PMID 11562499DOI 10.1073/PNAS.211268598 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2vdy SERPINA6 crystal structure of the reactive loop cleaved corticosteroid binding globulin complexed with cortisol 2.3Å AUTH A.ZHOU,Z.WEI,P.L.STANLEY,R.J.READ,P.E.STEIN,R.W.CARRELLTITL THE S-TO-R TRANSITION OF CORTICOSTEROID-BINDING GLOBULINTITL 2 AND THE MECHANISM OF HORMONE RELEASE.REF J.MOL.BIOL. V. 380 244 2008REFN ISSN 0022-2836PMID 18513745DOI 10.1016/J.JMB.2008.05.012 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]