General Structure Information
| PDB ID | 3f5n |
| HGNC Gene Label(s) | SERPINI1 |
| Structure Name | structure of native human neuroserpin |
| Resolution | 3.15Å |
| Reference | AUTH S.RICAGNO,S.CACCIA,G.SORRENTINO,G.ANTONINI,M.BOLOGNESITITL HUMAN NEUROSERPIN: STRUCTURE AND TIME-DEPENDENT INHIBITIONREF J.MOL.BIOL. V. 388 109 2009REFN ISSN 0022-2836PMID 19265707DOI 10.1016/J.JMB.2009.02.056 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 363 |
| Number Of SNVs | 87 |
| Number Of Permutations | 26117 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.024 |
| p-value | 0.676 |
ClinVar
| Number Of Residues | 363 |
| Number Of SNVs | 3 |
| Number Of Permutations | 277 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 1.0 |
| p-value | 0.011 |
COSMIC
| Number Of Residues | 363 |
| Number Of SNVs | 7 |
| Number Of Permutations | 2587 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.048 |
| p-value | 0.832 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 87 |
| Number Of ClinVar SNVs | 3 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.872 |
| p-value | 0.013 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 87 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | -0.08 |
| p-value | 0.908 |