General Structure Information 3odx ARHGEF1 crystal structure of an n-terminally truncated linker-dh/ph domains of p115-rhogef 3.2Å AUTH Z.CHEN,L.GUO,S.R.SPRANG,P.C.STERNWEISTITL MODULATION OF A GEF SWITCH: AUTOINHIBITION OF THE INTRINSICTITL 2 GUANINE NUCLEOTIDE EXCHANGE ACTIVITY OF P115-RHOREFREF PROTEIN SCI. V. 20 107 2011REFN ISSN 0961-8368 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2rgn ARHGEF25 crystal structure of p63rhogef complex with galpha-q and rhoa 3.5Å AUTH S.LUTZ,A.SHANKARANARAYANAN,C.COCO,M.RIDILLA,M.R.NANCE,AUTH 2 C.VETTEL,D.BALTUS,C.R.EVELYN,R.R.NEUBIG,T.WIELAND,J.J.TESMERTITL STRUCTURE OF GALPHAQ-P63RHOGEF-RHOA COMPLEX REVEALS ATITL 2 PATHWAY FOR THE ACTIVATION OF RHOA BY GPCRS.REF SCIENCE V. 318 1923 2007REFN ISSN 0036-8075PMID 18096806DOI 10.1126/SCIENCE.1147554 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 3t06 ARHGEF11 crystal structure of the dh/ph fragment of pdzrhogef with n-terminal regulatory elements in complex with human rhoa 2.84Å AUTH J.A.BIELNICKI,A.V.SHKUMATOV,U.DEREWENDA,A.V.SOMLYO,AUTH 2 D.I.SVERGUN,Z.S.DEREWENDATITL INSIGHTS INTO THE MOLECULAR ACTIVATION MECHANISM OF THETITL 2 RHOA-SPECIFIC GUANINE NUCLEOTIDE EXCHANGE FACTOR, PDZRHOGEF.REF J.BIOL.CHEM. V. 286 35163 2011REFN ISSN 0021-9258PMID 21816819DOI 10.1074/JBC.M111.270918 Variant Set Distributions Ripley’s […]