Assessment of Structural Intolerance and Durability
General Structure Information 2eho GINS2 crystal structure of human gins complex 3.0Å AUTH J.M.CHOI,H.S.LIM,J.J.KIM,O.K.SONG,Y.CHOTITL CRYSTAL STRUCTURE OF THE HUMAN GINS COMPLEXREF GENES DEV. V. 21 1316 2007REFN ISSN 0890-9369PMID 17545466DOI 10.1101/GAD.1548107 Variant Set Distributions Mapped Variants
General Structure Information 2i32 ASF1A structure of a human asf1a-hira complex and insights into specificity of histone chaperone complex assembly 2.7Å AUTH Y.TANG,M.V.POUSTOVOITOV,K.ZHAO,M.GARFINKEL,AUTH 2 A.CANUTESCU,R.DUNBRACK,P.D.ADAMS,R.MARMORSTEINTITL STRUCTURE OF A HUMAN ASF1A-HIRA COMPLEX ANDTITL 2 INSIGHTS INTO SPECIFICITY OF HISTONE CHAPERONETITL 3 COMPLEX ASSEMBLY.REF NAT.STRUCT.MOL.BIOL. V. 13 921 2006REFN ISSN 1545-9993PMID 16980972DOI 10.1038/NSMB1147 Variant Set Distributions Mapped […]
General Structure Information 3abd MAD2L2 structure of human rev7 in complex with a human rev3 fragment in a monoclinic crystal 1.9Å AUTH K.HARA,H.HASHIMOTO,Y.MURAKUMO,S.KOBAYASHI,T.KOGAME,S.UNZAI,AUTH 2 S.AKASHI,S.TAKEDA,T.SHIMIZU,M.SATOTITL CRYSTAL STRUCTURE OF HUMAN REV7 IN COMPLEX WITH A HUMAN REV3TITL 2 FRAGMENT AND STRUCTURAL IMPLICATION OF THE INTERACTIONTITL 3 BETWEEN DNA POLYMERASE {ZETA} AND REV1REF J.BIOL.CHEM. V. 285 12299 […]
General Structure Information 3gv7 POLI human dna polymerase iota in complex with t template dna and incoming dttp 2.2Å AUTH K.N.KIROUAC,H.LINGTITL STRUCTURAL BASIS OF ERROR-PRONE REPLICATION AND STALLING ATTITL 2 A THYMINE BASE BY HUMAN DNA POLYMERASE IOTAREF EMBO J. V. 28 1644 2009REFN ISSN 0261-4189PMID 19440206DOI 10.1038/EMBOJ.2009.122 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3in5 POLK structure of human dna polymerase kappa inserting datp opposite an 8-oxog dna lesion 3.2Å AUTH R.VASQUEZ-DEL CARPIO,T.D.SILVERSTEIN,S.LONE,AUTH 2 M.K.SWAN,J.R.CHOUDHURY,R.E.JOHNSON,S.PRAKASH,AUTH 3 L.PRAKASH,A.K.AGGARWALTITL STRUCTURE OF HUMAN DNA POLYMERASE KAPPA INSERTINGTITL 2 DATP OPPOSITE AN 8-OXOG DNA LESIONREF PLOS ONE V. 4 E5766 2009REFN ESSN 1932-6203PMID 19492058DOI 10.1371/JOURNAL.PONE.0005766 Variant Set Distributions Pathogenic Proximity […]
General Structure Information 2ebw REV1 solution structure of the brct domain from human dna repair protein rev1 -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE BRCT DOMAIN FROM HUMANTITL 2 DNA REPAIR PROTEIN REV1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2jw5 POLL polymerase lambda brct domain -1.0Å AUTH G.A.MUELLER,A.F.MOON,E.F.DEROSE,B.J.DAVIS,AUTH 2 D.A.RAMSDEN,L.C.PEDERSEN,R.E.LONDONTITL POLYMERASE LAMBDA BRCT DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2wvr CDT1 human cdt1:geminin complex 3.3Å AUTH V.DE MARCO,P.J.GILLESPIE,A.LI,N.KARANTZELIS,AUTH 2 E.CHRISTODOULOU,R.KLOMPMAKER,S.VAN GERWEN,A.FISH,AUTH 3 M.V.PETOUKHOV,M.S.ILIOU,Z.LYGEROU,R.H.MEDEMA,AUTH 4 J.J.BLOW,D.I.SVERGUN,S.TARAVIRAS,A.PERRAKISTITL QUATERNARY STRUCTURE OF THE HUMAN CDT1-GEMININTITL 2 COMPLEX REGULATES DNA REPLICATION LICENSING.REF PROC.NATL.ACAD.SCI.USA V. 106 19807 2009REFN ISSN 0027-8424PMID 19906994DOI 10.1073/PNAS.0905281106 Variant Set Distributions Mapped Variants
General Structure Information 2e9x GINS3 the crystal structure of human gins core complex 2.3Å AUTH K.KAMADA,Y.KUBOTA,T.ARATA,Y.SHINDO,F.HANAOKATITL STRUCTURE OF THE HUMAN GINS COMPLEX AND ITSTITL 2 ASSEMBLY AND FUNCTIONAL INTERFACE IN REPLICATIONTITL 3 INITIATIONREF NAT.STRUCT.MOL.BIOL. V. 14 388 2007REFN ISSN 1545-9993PMID 17417653DOI 10.1038/NSMB1231 Variant Set Distributions Mapped Variants
General Structure Information 2e9x GINS4 the crystal structure of human gins core complex 2.3Å AUTH K.KAMADA,Y.KUBOTA,T.ARATA,Y.SHINDO,F.HANAOKATITL STRUCTURE OF THE HUMAN GINS COMPLEX AND ITSTITL 2 ASSEMBLY AND FUNCTIONAL INTERFACE IN REPLICATIONTITL 3 INITIATIONREF NAT.STRUCT.MOL.BIOL. V. 14 388 2007REFN ISSN 1545-9993PMID 17417653DOI 10.1038/NSMB1231 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]