General Structure Information
| PDB ID | 2e9x |
| HGNC Gene Label(s) | GINS4 |
| Structure Name | the crystal structure of human gins core complex |
| Resolution | 2.3Å |
| Reference | AUTH K.KAMADA,Y.KUBOTA,T.ARATA,Y.SHINDO,F.HANAOKATITL STRUCTURE OF THE HUMAN GINS COMPLEX AND ITSTITL 2 ASSEMBLY AND FUNCTIONAL INTERFACE IN REPLICATIONTITL 3 INITIATIONREF NAT.STRUCT.MOL.BIOL. V. 14 388 2007REFN ISSN 1545-9993PMID 17417653DOI 10.1038/NSMB1231 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 197 |
| Number Of SNVs | 49 |
| Number Of Permutations | 14858 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.038 |
| p-value | 0.977 |
COSMIC
| Number Of Residues | 197 |
| Number Of SNVs | 3 |
| Number Of Permutations | 96 |
| Optimal Distance Threshold | 42.0 |
| K Statistic | 0.333 |
| p-value | 0.208 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 49 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 33.0 |
| K Statistic | -0.678 |
| p-value | 0.089 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
