Assessment of Structural Intolerance and Durability
General Structure Information 2eqo TRAF3IP1 solution structure of the stn_traf3ip1_nd domain of interleukin 13 receptor alpha 1-binding protein-1 [homo sapiens] -1.0Å AUTH W.DANG,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE STN_TRAF3IP1_ND DOMAINTITL 2 OF INTERLEUKIN 13 RECEPTOR ALPHA 1-BINDINGTITL 3 PROTEIN-1 [HOMO SAPIENS]REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3p2t LILRB4 crystal structure of leukocyte ig-like receptor lilrb4 (ilt3/lir- 5/cd85k) 1.7Å AUTH H.CHENG,F.MOHAMMED,G.NAM,Y.CHEN,J.QI,L.I.GARNER,R.L.ALLEN,AUTH 2 J.YAN,B.E.WILLCOX,G.F.GAOTITL CRYSTAL STRUCTURE OF LEUKOCYTE IG-LIKE RECEPTOR LILRB4TITL 2 (ILT3/LIR-5/CD85K): A MYELOID INHIBITORY RECEPTOR INVOLVEDTITL 3 IN IMMUNE TOLERANCEREF J.BIOL.CHEM. V. 286 18013 2011REFN ISSN 0021-9258PMID 21454581DOI 10.1074/JBC.M111.221028 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 4bkf EFNB3 crystal structure of the human epha4 ectodomain in complex with human ephrinb3 4.65Å AUTH E.SEIRADAKE,A.SCHAUPP,D.DEL TORO RUIZ,R.KAUFMANN,AUTH 2 N.MITAKIDIS,K.HARLOS,A.R.ARICESCU,R.KLEIN,E.Y.JONESTITL STRUCTURALLY ENCODED INTRACLASS DIFFERENCES IN EPHATITL 2 CLUSTERS DRIVE DISTINCT CELL RESPONSESREF NAT.STRUCT.MOL.BIOL. V. 20 958 2013REFN ISSN 1545-9993PMID 23812375DOI 10.1038/NSMB.2617 Variant Set Distributions Mapped Variants
General Structure Information 2prg NCOA1 ligand-binding domain of the human peroxisome proliferator activated receptor gamma 2.3Å AUTH R.T.NOLTE,G.B.WISELY,S.WESTIN,J.E.COBB,M.H.LAMBERT,AUTH 2 R.KUROKAWA,M.G.ROSENFELD,T.M.WILLSON,C.K.GLASS,AUTH 3 M.V.MILBURNTITL LIGAND BINDING AND CO-ACTIVATOR ASSEMBLY OF THETITL 2 PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA.REF NATURE V. 395 137 1998REFN ISSN 0028-0836PMID 9744270DOI 10.1038/25931 Variant Set Distributions Mapped Variants
General Structure Information 4doh IL20RB il20/il201/il20r2 ternary complex 2.8Å AUTH N.J.LOGSDON,A.DESHPANDE,B.D.HARRIS,K.R.RAJASHANKAR,AUTH 2 M.R.WALTERTITL STRUCTURAL BASIS FOR RECEPTOR SHARING AND ACTIVATION BYTITL 2 INTERLEUKIN-20 RECEPTOR-2 (IL-20R2) BINDING CYTOKINES.REF PROC.NATL.ACAD.SCI.USA V. 109 12704 2012REFN ISSN 0027-8424PMID 22802649DOI 10.1073/PNAS.1117551109 Variant Set Distributions Mapped Variants
General Structure Information 4dkd IL34 crystal structure of human interleukin-34 bound to human csf-1r 3.0Å AUTH X.MA,W.Y.LIN,Y.CHEN,S.STAWICKI,K.MUKHYALA,Y.WU,F.MARTIN,AUTH 2 J.F.BAZAN,M.A.STAROVASNIKTITL STRUCTURAL BASIS FOR THE DUAL RECOGNITION OF HELICALTITL 2 CYTOKINES IL-34 AND CSF-1 BY CSF-1R.REF STRUCTURE V. 20 676 2012REFN ISSN 0969-2126PMID 22483114DOI 10.1016/J.STR.2012.02.010 Variant Set Distributions Mapped Variants
General Structure Information 3aqf CALCRL crystal structure of the human crlr/ramp2 extracellular complex 2.6Å AUTH S.KUSANO,M.KUKIMOTO-NIINO,N.HINO,N.OHSAWA,K.OKUDA,AUTH 2 K.SAKAMOTO,M.SHIROUZU,T.SHINDO,S.YOKOYAMATITL STRUCTURAL BASIS FOR EXTRACELLULAR INTERACTIONS BETWEENTITL 2 CALCITONIN RECEPTOR-LIKE RECEPTOR AND RECEPTORTITL 3 ACTIVITY-MODIFYING PROTEIN 2 FOR ADRENOMEDULLIN-SPECIFICTITL 4 BINDINGREF PROTEIN SCI. V. 21 199 2012REFN ISSN 0961-8368PMID 22102369DOI 10.1002/PRO.2003 Variant Set Distributions Mapped Variants
General Structure Information 2vns STEAP3 crystal structure of the membrane proximal oxidoreductase domain of human steap3, the dominant ferric reductase of the erythroid transferrin cycle 2.0Å AUTH A.K.SENDAMARAI,R.S.OHGAMI,M.D.FLEMING,C.M.LAWRENCETITL STRUCTURE OF THE MEMBRANE PROXIMAL OXIDOREDUCTASETITL 2 DOMAIN OF HUMAN STEAP3, THE DOMINANTTITL 3 FERRIREDUCTASE OF THE ERYTHROID TRANSFERRIN CYCLEREF PROC.NATL.ACAD.SCI.USA V. 105 7410 2008REFN ISSN 0027-8424PMID […]
General Structure Information 3ucr TIGIT crystal structure of the immunoreceptor tigit igv domain 2.63Å AUTH K.F.STENGEL,K.HARDEN-BOWLES,X.YU,L.ROUGE,J.YIN,AUTH 2 L.COMPS-AGRAR,C.WIESMANN,J.F.BAZAN,D.L.EATON,J.L.GROGANTITL STRUCTURE OF TIGIT IMMUNORECEPTOR BOUND TO POLIOVIRUSTITL 2 RECEPTOR REVEALS A CELL-CELL ADHESION AND SIGNALINGTITL 3 MECHANISM THAT REQUIRES CIS-TRANS RECEPTOR CLUSTERING.REF PROC.NATL.ACAD.SCI.USA V. 109 5399 2012REFN ISSN 0027-8424PMID 22421438DOI 10.1073/PNAS.1120606109 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 4hsa IL17A structure of interleukin 17a in complex with il17ra receptor 3.15Å AUTH S.LIU,X.SONG,B.A.CHRUNYK,S.SHANKER,L.R.HOTH,E.S.MARR,AUTH 2 M.C.GRIFFORTITL CRYSTAL STRUCTURES OF INTERLEUKIN 17A AND ITS COMPLEX WITHTITL 2 IL-17 RECEPTOR A.REF NAT COMMUN V. 4 1888 2013REFN ESSN 2041-1723PMID 23695682DOI 10.1038/NCOMMS2880 Variant Set Distributions Mapped Variants