4DKD.A | IL34

General Structure Information

PDB ID 4dkd
HGNC Gene Label(s) IL34
Structure Name crystal structure of human interleukin-34 bound to human csf-1r
Resolution 3.0Å
Reference AUTH X.MA,W.Y.LIN,Y.CHEN,S.STAWICKI,K.MUKHYALA,Y.WU,F.MARTIN,AUTH 2 J.F.BAZAN,M.A.STAROVASNIKTITL STRUCTURAL BASIS FOR THE DUAL RECOGNITION OF HELICALTITL 2 CYTOKINES IL-34 AND CSF-1 BY CSF-1R.REF STRUCTURE V. 20 676 2012REFN ISSN 0969-2126PMID 22483114DOI 10.1016/J.STR.2012.02.010

Variant Set Distributions

ExAC Variants

Number Of Residues 161
Number Of SNVs 39
Number Of Permutations 3359
Optimal Distance Threshold 6.0
K Statistic 0.042
p-value 0.81

Mapped Variants

[+] ExAC Missense Variants