Assessment of Structural Intolerance and Durability
General Structure Information 2ekh SH3PXD2A solution structures of the sh3 domain of human kiaa0418 -1.0Å AUTH M.SATO,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURES OF THE SH3 DOMAIN OF HUMANTITL 2 KIAA0418REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yqp DDX59 solution structure of the zf-hit domain in dead (asp-glu- ala-asp) box polypeptide 59 -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TARADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZF-HIT DOMAIN IN DEADTITL 2 (ASP-GLU-ALA-ASP) BOX POLYPEPTIDE 59REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2enk SLC30A9 solution structure of a putativ dna-binding domain of the humansolute carrier family 30 (zinc transporter) protein -1.0Å AUTH A.K.GORONCY,N.TOCHIO,T.TOMIZAWA,S.KOSHIBA,AUTH 2 S.WATANABE,T.HARADA,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF A PUTATIV DNA-BINDING DOMAINTITL 2 OF THE HUMANSOLUTE CARRIER FAMILY 30 (ZINCTITL 3 TRANSPORTER) PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3u21 NFRKB crystal structure of a fragment of nuclear factor related to kappa-b- binding protein (residues 370-495) (nfrkb) from homo sapiens at 2.18 a resolution 2.18Å AUTH A.KUMAR,S.MOCKLINGHOFF,F.YUMOTO,L.JAROSZEWSKI,C.L.FARR,AUTH 2 A.GRZECHNIK,P.NGUYEN,C.X.WEICHENBERGER,H.J.CHIU,H.E.KLOCK,AUTH 3 M.A.ELSLIGER,A.M.DEACON,A.GODZIK,S.A.LESLEY,B.R.CONKLIN,AUTH 4 R.J.FLETTERICK,I.A.WILSONTITL STRUCTURE OF A NOVEL WINGED-HELIX LIKE DOMAIN FROM HUMANTITL 2 NFRKB PROTEIN.REF PLOS ONE V. 7 43761 2012REFN […]
General Structure Information 3i8e DDB1 crystal structure of ddb1 in complex with the h-box motif of wdr42a 3.4Å AUTH T.LI,E.I.ROBERT,P.C.VAN BREUGEL,M.STRUBIN,N.ZHENGTITL A PROMISCUOUS ALPHA-HELICAL MOTIF ANCHORS VIRAL HIJACKERSTITL 2 AND SUBSTRATE RECEPTORS TO THE CUL4-DDB1 UBIQUITIN LIGASETITL 3 MACHINERY.REF NAT.STRUCT.MOL.BIOL. V. 17 105 2010REFN ISSN 1545-9993PMID 19966799DOI 10.1038/NSMB.1719 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 4a4i LIN28B crystal structure of the human lin28b cold shock domain 1.95Å AUTH F.MAYR,A.SCHUTZ,N.DOGE,U.HEINEMANNTITL THE LIN28 COLD-SHOCK DOMAIN REMODELS PRE-LET-7 MICRORNA.REF NUCLEIC ACIDS RES. V. 40 7492 2012REFN ISSN 0305-1048PMID 22570413DOI 10.1093/NAR/GKS355 Variant Set Distributions Mapped Variants
General Structure Information 2e0a PDK4 crystal structure of human pyruvate dehydrogenase kinase 4 in complex with amppnp 1.86Å AUTH M.KUKIMOTO-NIINO,A.TOKMAKOV,T.TERADA,N.OHBAYASHI,T.FUJIMOTO,AUTH 2 S.GOMI,I.SHIROMIZU,M.KAWAMOTO,T.MATSUSUE,M.SHIROUZU,AUTH 3 S.YOKOYAMATITL INHIBITOR-BOUND STRUCTURES OF HUMAN PYRUVATE DEHYDROGENASETITL 2 KINASE 4.REF ACTA CRYSTALLOGR.,SECT.D V. 67 763 2011REFN ISSN 0907-4449PMID 21904029DOI 10.1107/S090744491102405X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 2d8s MARCH8 solution structure of the ring domain of the human cellular modulator of immune recognition protein -1.0Å AUTH K.MIYAMOTO,T.KIGAWA,T.TOMIZAWA,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RING DOMAIN OF THE HUMANTITL 2 CELLULAR MODULATOR OF IMMUNE RECOGNITION PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 2edv FRMPD1 solution structure of the pdz domain from human ferm and pdz domain containing 1 -1.0Å AUTH K.SEIMIYA,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PDZ DOMAIN FROM HUMANTITL 2 FERM AND PDZ DOMAIN CONTAINING 1REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2edr OBSCN solution structure of the ig-like domain (3361-3449) of human obscurin -1.0Å AUTH C.KUROSAKI,K.IZUMI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE IG-LIKE DOMAINTITL 2 (3361-3449) OF HUMAN OBSCURINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants