Assessment of Structural Intolerance and Durability
General Structure Information 2vm8 DPYSL2 human crmp-2 crystallised in the presence of mg 1.9Å AUTH V.MAJAVA,N.LOYTYNOJA,W.Q.CHEN,G.LUBEC,P.KURSULATITL CRYSTAL AND SOLUTION STRUCTURE, STABILITY ANDTITL 2 POST- TRANSLATIONAL MODIFICATIONS OF COLLAPSINTITL 3 RESPONSE MEDIATOR PROTEIN 2.REF FEBS J. V. 275 4583 2008REFN ISSN 1742-464XPMID 18699782DOI 10.1111/J.1742-4658.2008.06601.X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 4kbs GLTPD1 crystal structure of human ceramide-1-phosphate transfer protein (cptp) in complex with 12:0 phosphatidic acid (12:0 pa) 1.9Å AUTH D.K.SIMANSHU,R.K.KAMLEKAR,D.S.WIJESINGHE,X.ZOU,X.ZHAI,AUTH 2 S.K.MISHRA,J.G.MOLOTKOVSKY,L.MALININA,E.H.HINCHCLIFFE,AUTH 3 C.E.CHALFANT,R.E.BROWN,D.J.PATELTITL NON-VESICULAR TRAFFICKING BY A CERAMIDE-1-PHOSPHATE TRANSFERTITL 2 PROTEIN REGULATES EICOSANOIDS.REF NATURE V. 500 463 2013REFN ISSN 0028-0836PMID 23863933DOI 10.1038/NATURE12332 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 4orh UBE2V2 crystal structure of rnf8 bound to the ubc13/mms2 heterodimer 4.8Å AUTH S.J.CAMPBELL,R.A.EDWARDS,C.C.LEUNG,D.NECULAI,C.D.HODGE,AUTH 2 S.DHE-PAGANON,J.N.GLOVERTITL MOLECULAR INSIGHTS INTO THE FUNCTION OF RING FINGERTITL 2 (RNF)-CONTAINING PROTEINS HRNF8 AND HRNF168 INTITL 3 UBC13/MMS2-DEPENDENT UBIQUITYLATION.REF J.BIOL.CHEM. V. 287 23900 2012REFN ISSN 0021-9258PMID 22589545DOI 10.1074/JBC.M112.359653 Variant Set Distributions Mapped Variants
General Structure Information 1wf5 SDK2 solution structure of the first fn3 domain of sidekick-2 protein -1.0Å AUTH X.QIN,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST FN3 DOMAIN OFTITL 2 SIDEKICK-2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2edq OBSCN solution structure of the ig-like domain (3713-3806) of human obscurin -1.0Å AUTH K.IZUMI,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE IG-LIKE DOMAINTITL 2 (3713-3806) OF HUMAN OBSCURINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1hy9 CARTPT cocaine and amphetamine regulated transcript -1.0Å AUTH S.LUDVIGSEN,L.THIM,A.M.BLOM,B.S.WULFFTITL SOLUTION STRUCTURE OF THE SATIETY FACTOR, CART,TITL 2 REVEALS NEW FUNCTIONALITY OF A WELL-KNOWN FOLD.REF BIOCHEMISTRY V. 40 9082 2001REFN ISSN 0006-2960PMID 11478874DOI 10.1021/BI010433U Variant Set Distributions Mapped Variants
General Structure Information 1wig ABLIM2 solution structure of rsgi ruh-019, a lim domain of actin binding lim protein 2 (kiaa1808 protein) from human cdna -1.0Å AUTH T.ABE,H.HIROTA,S.KOSHIBA,T.KIGAWA,F.HAYASHI,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-019, A LIM DOMAINTITL 2 OF ACTIN BINDING LIM PROTEIN 2 (KIAA1808 PROTEIN)TITL 3 FROM HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set […]
General Structure Information 1×68 FHL5 solution structures of the c-terminal lim domain of human fhl5 protein -1.0Å AUTH N.NAMEKI,A.SASAGAWA,M.SATO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE C-TERMINAL LIM DOMAINTITL 2 OF HUMAN FHL5 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2e5s MBNL2 solution structure of the zf-ccchx2 domain of muscleblind- like 2, isoform 1 [homo sapiens] -1.0Å AUTH F.HE,W.DANG,C.ABE,K.TSUDA,M.INOUE,S.WATANABE,AUTH 2 N.KOBAYASHI,T.KIGAWA,T.MATSUDA,T.YABUKI,M.AOKI,AUTH 3 E.SEKI,T.HARADA,Y.TOMABECHI,T.TERADA,M.SHIROUZU,AUTH 4 A.TANAKA,P.GUNTERT,Y.MUTO,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA BINDING DOMAIN INTITL 2 THE HUMAN MUSCLEBLIND-LIKE PROTEIN 2REF PROTEIN SCI. V. 18 80 2009REFN ISSN 0961-8368PMID 19177353DOI 10.1002/PRO.17 Variant Set Distributions […]
General Structure Information 3dai ATAD2 crystal structure of the bromodomain of the human atad2 1.95Å AUTH P.FILIPPAKOPOULOS,S.PICAUD,M.MANGOS,T.KEATES,J.P.LAMBERT,AUTH 2 D.BARSYTE-LOVEJOY,I.FELLETAR,R.VOLKMER,S.MULLER,T.PAWSON,AUTH 3 A.C.GINGRAS,C.H.ARROWSMITH,S.KNAPPTITL HISTONE RECOGNITION AND LARGE-SCALE STRUCTURAL ANALYSIS OFTITL 2 THE HUMAN BROMODOMAIN FAMILY.REF CELL(CAMBRIDGE,MASS.) V. 149 214 2012REFN ISSN 0092-8674PMID 22464331DOI 10.1016/J.CELL.2012.02.013 Variant Set Distributions Mapped Variants