Assessment of Structural Intolerance and Durability
General Structure Information 2edt OBSCN solution structure of the ig-like domain (3449-3537) from human obscurin -1.0Å AUTH K.SEIMIYA,K IZUMI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE IG-LIKE DOMAINTITL 2 (3449-3537) FROM HUMAN OBSCURINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ox8 COLEC12 human scavenger receptor c-type lectin carbohydrate- recognition domain. 2.5Å AUTH H.FEINBERG,M.E.TAYLOR,W.I.WEISTITL SCAVENGER RECEPTOR C-TYPE LECTIN BINDS TO THETITL 2 LEUKOCYTE CELL SURFACE GLYCAN LEWIS(X) BY A NOVELTITL 3 MECHANISM.REF J.BIOL.CHEM. V. 282 17250 2007REFN ISSN 0021-9258PMID 17420244DOI 10.1074/JBC.M701624200 Variant Set Distributions Mapped Variants
General Structure Information 2mdg ZNF423 solution nmr structure of zinc finger protein 423 from homo sapiens, northeast structural genomics consortium (nesg) target hr7298f -1.0Å AUTH K.PEDERSON,D.LEE,E.KOHAN,H.JANJUA,R.XIAO,J.K.EVERETT,AUTH 2 T.B.ACTON,G.T.MONTELIONE,J.H.PRESTEGARDTITL SOLUTION NMR STRUCTURE OF ZINC FINGER PROTEIN 423 FROM HOMOTITL 2 SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG)TITL 3 TARGET HR7298FREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]
General Structure Information 2vpj KLHL12 crystal structure of the kelch domain of human klhl12 1.85Å AUTH P.CANNING,C.D.O.COOPER,T.KROJER,J.W.MURRAY,A.C.W.PIKE,AUTH 2 A.CHAIKUAD,T.KEATES,C.THANGARATNARAJAH,V.HOJZAN,B.D.MARSDEN,AUTH 3 O.GILEADI,S.KNAPP,F.VON DELFT,A.N.BULLOCKTITL STRUCTURAL BASIS FOR CUL3 ASSEMBLY WITH THE BTB-KELCHTITL 2 FAMILY OF E3 UBIQUITIN LIGASES.REF J.BIOL.CHEM. V. 288 7803 2013REFN ISSN 0021-9258PMID 23349464DOI 10.1074/JBC.M112.437996 Variant Set Distributions Mapped Variants
General Structure Information 3qbv ITSN1 structure of designed orthogonal interaction between cdc42 and nucleotide exchange domains of intersectin 2.65Å AUTH G.T.KAPP,S.LIU,A.STEIN,D.T.WONG,A.REMENYI,B.J.YEH,AUTH 2 J.S.FRASER,J.TAUNTON,W.A.LIM,T.KORTEMMETITL CONTROL OF PROTEIN SIGNALING USING A COMPUTATIONALLYTITL 2 DESIGNED GTPASE/GEF ORTHOGONAL PAIR.REF PROC.NATL.ACAD.SCI.USA V. 109 5277 2012REFN ISSN 0027-8424PMID 22403064DOI 10.1073/PNAS.1114487109 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 4gn1 RAPH1 crystal structure of the ra and ph domains of lamellipodin 2.4Å AUTH Y.C.CHANG,H.ZHANG,M.L.BRENNAN,J.WUTITL CRYSTAL STRUCTURE OF LAMELLIPODIN IMPLICATES DIVERSETITL 2 FUNCTIONS IN ACTIN POLYMERIZATION AND RAS SIGNALING.REF PROTEIN CELL V. 4 211 2013REFN ISSN 1674-800XPMID 23483482DOI 10.1007/S13238-013-2082-5 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 4hbd KANK2 crystal structure of kank2 ankyrin repeats 1.72Å AUTH C.XU,W.TEMPEL,T.CEROVINA,M.EL BAKKOURI,C.BOUNTRA,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,J.MINTITL CRYSTAL STRUCTURE OF KANK2 ANKYRIN REPEATSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ep6 MCTP2 solution structure of the second c2 domain from human mctp2 protein -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND C2 DOMAIN FROMTITL 2 HUMAN MCTP2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3o46 MPP7 crystal structure of the pdz domain of mpp7 1.3Å AUTH L.NEDYALKOVA,Y.TONG,W.TEMPEL,N.ZHONG,X.GUAN,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,AUTH 3 H.PARKTITL CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF MPP7REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2rpp MBNL2 solution structure of tandem zinc finger domain 12 in muscleblind-like protein 2 -1.0Å AUTH F.HE,W.DANG,C.ABE,K.TSUDA,M.INOUE,S.WATANABE,AUTH 2 N.KOBAYASHI,T.KIGAWA,T.MATSUDA,T.YABUKI,M.AOKI,AUTH 3 E.SEKI,T.HARADA,Y.TOMABECHI,T.TERADA,M.SHIROUZU,AUTH 4 A.TANAKA,P.GUNTERT,Y.MUTO,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA BINDING DOMAIN INTITL 2 THE HUMAN MUSCLEBLIND-LIKE PROTEIN 2REF PROTEIN SCI. V. 18 80 2009REFN ISSN 0961-8368PMID 19177353DOI 10.1002/PRO.17 Variant Set Distributions Mapped Variants