General Structure Information
| PDB ID | 4gn1 |
| HGNC Gene Label(s) | RAPH1 |
| Structure Name | crystal structure of the ra and ph domains of lamellipodin |
| Resolution | 2.4Å |
| Reference | AUTH Y.C.CHANG,H.ZHANG,M.L.BRENNAN,J.WUTITL CRYSTAL STRUCTURE OF LAMELLIPODIN IMPLICATES DIVERSETITL 2 FUNCTIONS IN ACTIN POLYMERIZATION AND RAS SIGNALING.REF PROTEIN CELL V. 4 211 2013REFN ISSN 1674-800XPMID 23483482DOI 10.1007/S13238-013-2082-5 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 240 |
| Number Of SNVs | 48 |
| Number Of Permutations | 16669 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.123 |
| p-value | 0.557 |
COSMIC
| Number Of Residues | 240 |
| Number Of SNVs | 3 |
| Number Of Permutations | 379 |
| Optimal Distance Threshold | 39.0 |
| K Statistic | 0.333 |
| p-value | 0.096 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
