Assessment of Structural Intolerance and Durability
General Structure Information 2dlu INADL solution structure of the second pdz domain of human inad- like protein -1.0Å AUTH K.INOUE,C.KUROSAKI,K.IZUMI,M.YOSHIDA,F.HAYASHI,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND PDZ DOMAIN OFTITL 2 HUMAN INAD-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4h8s APPL2 crystal structure of human appl2barph domain 3.5Å AUTH G.J.KING,J.STOCKLI,S.H.HU,B.WINNEN,W.G.DUPREZ,C.C.MEOLI,AUTH 2 J.R.JUNUTULA,R.J.JARROTT,D.E.JAMES,A.E.WHITTEN,J.L.MARTINTITL MEMBRANE CURVATURE PROTEIN EXHIBITS INTERDOMAIN FLEXIBILITYTITL 2 AND BINDS A SMALL GTPASE.REF J.BIOL.CHEM. V. 287 40996 2012REFN ISSN 0021-9258PMID 23055524DOI 10.1074/JBC.M112.349803 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2d93 RAPGEF6 solution structure of the cnmp_binding domain of human rap guanine nucleotide exchange factor 6 -1.0Å AUTH K.INOUE,Y.MUTO,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CNMP_BINDING DOMAIN OFTITL 2 HUMAN RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 6REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2co8 MICAL1 solution structures of the lim domain of human nedd9 interacting protein with calponin homology and lim domains -1.0Å AUTH M.SATO,T.TOMIZAWA,K.SAITO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE LIM DOMAIN OF HUMANTITL 2 NEDD9 INTERACTING PROTEIN WITH CALPONIN HOMOLOGYTITL 3 AND LIM DOMAINSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2cs4 RASSF8 solution structure of n-terminal domain of chromosome 12 open reading frame 2 -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF N-TERMINAL DOMAIN OFTITL 2 CHROMOSOME 12 OPEN READING FRAME 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dnl CPEB3 solution structure of rna binding domain in cytoplasmic polyadenylation element binding protein 3 -1.0Å AUTH K.TSUDA,T.NAGATA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN INTITL 2 CYTOPLASMIC POLYADENYLATION ELEMENT BINDINGTITL 3 PROTEIN 3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dk9 MICAL1 solution structure of calponin homology domain of human mical-1 -1.0Å AUTH H.SUN,H.DAI,J.ZHANG,X.JIN,S.XIONG,J.XU,J.WU,Y.SHITITL SOLUTION STRUCTURE OF CALPONIN HOMOLOGY DOMAIN OFTITL 2 HUMAN MICAL-1REF J.BIOMOL.NMR V. 36 295 2006REFN ISSN 0925-2738PMID 17043746DOI 10.1007/S10858-006-9062-5 Variant Set Distributions Mapped Variants
General Structure Information 3o7x PIWIL2 crystal structure of human hili paz domain 2.92Å AUTH Y.TIAN,D.K.SIMANSHU,J.B.MA,D.J.PATELTITL INAUGURAL ARTICLE: STRUCTURAL BASIS FOR PIRNATITL 2 2-O-METHYLATED 3-END RECOGNITION BY PIWI PAZTITL 3 (PIWI/ARGONAUTE/ZWILLE) DOMAINS.REF PROC.NATL.ACAD.SCI.USA V. 108 903 2011REFN ISSN 0027-8424PMID 21193640DOI 10.1073/PNAS.1017762108 Variant Set Distributions Mapped Variants
General Structure Information 2hup RAB43 crystal structure of human rab43 in complex with gdp 2.05Å AUTH J.WANG,Y.SHEN,W.TEMPEL,R.LANDRY,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,AUTH 3 H.PARKTITL CRYSTAL STRUCTURE OF HUMAN RAB43 IN COMPLEX WITHTITL 2 GDPREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3cuq VPS36 integrated structural and functional model of the human escrt-ii complex 2.61Å AUTH Y.J.IM,J.H.HURLEYTITL INTEGRATED STRUCTURAL MODEL AND MEMBRANE TARGETING MECHANISMTITL 2 OF THE HUMAN ESCRT-II COMPLEXREF DEV.CELL V. 14 902 2008REFN ISSN 1534-5807PMID 18539118DOI 10.1016/J.DEVCEL.2008.04.004 Variant Set Distributions Mapped Variants