Assessment of Structural Intolerance and Durability
General Structure Information 3s4e DUSP19 crystal structrue of a novel mitogen-activated protein kinase phosphatase, skrp1 1.26Å AUTH C.H.WEI,S.Y.RYU,Y.H.JEON,M.Y.YOON,D.G.JEONG,S.J.KIM,S.E.RYUTITL CRYSTAL STRUCTURE OF A NOVEL MITOGEN-ACTIVATED PROTEINTITL 2 KINASE PHOSPHATASE, SKRP1.REF PROTEINS V. 79 3242 2011REFN ISSN 0887-3585PMID 21989941DOI 10.1002/PROT.23156 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1uew MAGI2 solution structure of the forth pdz domain of human atrophin-1 interacting protein 1 (kiaa0705 protein) -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FORTH PDZ DOMAIN OFTITL 2 HUMAN ATROPHIN-1 INTERACTING PROTEIN 1 (KIAA0705TITL 3 PROTEIN)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1x4p SUGP2 solution structure of surp domain in sfrs14 protei -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF SURP DOMAIN IN SFRS14 PROTEIREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4aqi S100A7A structure of human s100a15 bound to zinc and calcium 1.7Å AUTH J.I.MURRAY,M.L.TONKIN,A.L.WHITING,F.PENG,B.FARNELL,AUTH 2 J.T.CULLEN,F.HOF,M.J.BOULANGERTITL STRUCTURAL CHARACTERIZATION OF S100A15 REVEALS A NOVEL ZINCTITL 2 COORDINATION SITE AMONG S100 PROTEINS AND ALTERED SURFACETITL 3 CHEMISTRY WITH FUNCTIONAL IMPLICATIONS FOR RECEPTORTITL 4 BINDING.REF BMC STRUCT.BIOL. V. 12 16 2012REFN ISSN 1472-6807PMID 22747601DOI 10.1186/1472-6807-12-16 […]
General Structure Information 2csy RNF113B solution structure of the ring domain of the zinc finger protein 183-like 1 -1.0Å AUTH K.MIYAMOTO,M.SATO,T.TOMIZAWA,K.SAITO,S.KOSHIBA,AUTH 2 M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RING DOMAIN OF THE ZINCTITL 2 FINGER PROTEIN 183-LIKE 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dmx DNAJB8 solution structure of the j domain of dnaj homolog subfamily b member 8 -1.0Å AUTH S.OHNISHI,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE J DOMAIN OF DNAJ HOMOLOGTITL 2 SUBFAMILY B MEMBER 8REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2xqn ENAH complex of the 2nd and 3rd lim domains of tes with the evh1 domain of mena and the n-terminal domain of actin-like protein arp7a 2.62Å AUTH B.BOEDA,P.P.KNOWLES,D.C.BRIGGS,J.MURRAY-RUST,E.SORIANO,AUTH 2 B.K.GARVALOV,N.Q.MCDONALD,M.WAYTITL MOLECULAR RECOGNITION OF THE TES LIM2-3 DOMAINS BY THETITL 2 ACTIN-RELATED PROTEIN ARP7A.REF J.BIOL.CHEM. V. 286 11543 2011REFN ISSN 0021-9258PMID 21278383DOI […]
General Structure Information 1va9 DSCAML1 solution structure of the second fniii domain of dscaml1 protein -1.0Å AUTH X.-R.QIN,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND FNIII DOMAIN OFTITL 2 DSCAML1 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2pnt GRASP crystal structure of the pdz domain of human grasp (grp1) in complex with the c-terminal peptide of the metabotropic glutamate receptor type 1 2.15Å AUTH J.ELKINS,E.PAPAGRIGORIOU,C.COOPER,C.GILEADI,AUTH 2 J.UPPENBERG,J.BRAY,F.VON DELFT,A.C.W.PIKE,AUTH 3 E.UGOCHUKWU,C.UMEANO,O.GILEADI,A.EDWARDS,AUTH 4 C.H.ARROWSMITH,J.WEIGELT,M.SUNDSTROM,D.A.DOYLE,AUTH 5 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMAN GRASPTITL 2 (GRP1) IN […]
General Structure Information 2eef PPP1R3B solution structure of the cbm_21 domain from human protein phosphatase 1, regulatory (inhibitor) subunit 3b -1.0Å AUTH T.TOMIZAWA,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CBM_21 DOMAIN FROM HUMANTITL 2 PROTEIN PHOSPHATASE 1, REGULATORY (INHIBITOR)TITL 3 SUBUNIT 3BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants