General Structure Information
| PDB ID | 3s4e |
| HGNC Gene Label(s) | DUSP19 |
| Structure Name | crystal structrue of a novel mitogen-activated protein kinase phosphatase, skrp1 |
| Resolution | 1.26Å |
| Reference | AUTH C.H.WEI,S.Y.RYU,Y.H.JEON,M.Y.YOON,D.G.JEONG,S.J.KIM,S.E.RYUTITL CRYSTAL STRUCTURE OF A NOVEL MITOGEN-ACTIVATED PROTEINTITL 2 KINASE PHOSPHATASE, SKRP1.REF PROTEINS V. 79 3242 2011REFN ISSN 0887-3585PMID 21989941DOI 10.1002/PROT.23156 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 142 |
| Number Of SNVs | 39 |
| Number Of Permutations | 16244 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.116 |
| p-value | 0.717 |
COSMIC
| Number Of Residues | 142 |
| Number Of SNVs | 4 |
| Number Of Permutations | 66 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.167 |
| p-value | 0.412 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 39 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.456 |
| p-value | 0.845 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
