Assessment of Structural Intolerance and Durability
General Structure Information 2zme SNF8 integrated structural and functional model of the human escrt-ii complex 2.9Å AUTH Y.J.IM,J.H.HURLEYTITL INTEGRATED STRUCTURAL MODEL AND MEMBRANE TARGETING MECHANISMTITL 2 OF THE HUMAN ESCRT-II COMPLEXREF DEV.CELL V. 14 902 2008REFN ISSN 1534-5807PMID 18539118DOI 10.1016/J.DEVCEL.2008.04.004 Variant Set Distributions Mapped Variants
General Structure Information 3siu PRPF31 structure of a hprp31-15.5k-u4atac 5 stem loop complex, monomeric form 2.63Å AUTH S.LIU,H.GHALEI,R.LUHRMANN,M.C.WAHLTITL STRUCTURAL BASIS FOR THE DUAL U4 AND U4ATAC SNRNA-BINDINGTITL 2 SPECIFICITY OF SPLICEOSOMAL PROTEIN HPRP31.REF RNA V. 17 1655 2011REFN ISSN 1355-8382PMID 21784869DOI 10.1261/RNA.2690611 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2f8v TTN structure of full length telethonin in complex with the n-terminus of titin 2.75Å AUTH N.PINOTSIS,M.PETOUKHOV,S.LANGE,D.SVERGUN,P.ZOU,M.GAUTEL,AUTH 2 M.WILMANNSTITL EVIDENCE FOR A DIMERIC ASSEMBLY OF TWO TITIN/TELETHONINTITL 2 COMPLEXES INDUCED BY THE TELETHONIN C-TERMINUS.REF J.STRUCT.BIOL. V. 155 239 2006REFN ISSN 1047-8477PMID 16713295DOI 10.1016/J.JSB.2006.03.028 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2izv SOCS4 crystal structure of socs-4 in complex with elongin-b and elongin-c at 2.55a resolution 2.55Å AUTH A.N.BULLOCK,M.C.RODRIGUEZ,J.E.DEBRECZENI,Z.SONGYANG,S.KNAPPTITL STRUCTURE OF THE SOCS4-ELONGINB/C COMPLEX REVEALS ATITL 2 DISTINCT SOCS BOX INTERFACE AND THE MOLECULAR BASIS FORTITL 3 SOCS-DEPENDENT EGFR DEGRADATION.REF STRUCTURE V. 15 1493 2007REFN ISSN 0969-2126PMID 17997974DOI 10.1016/J.STR.2007.09.016 Variant Set Distributions Mapped […]
General Structure Information 2edi UBE2F solution structure of the uq_con domain from human nedd8- conjugating enzyme nce2 -1.0Å AUTH H.ENDO,K.IZUMI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE UQ_CON DOMAIN FROM HUMANTITL 2 NEDD8-CONJUGATING ENZYME NCE2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2wwm TTN crystal structure of the titin m10-obscurin like 1 ig complex in space group p1 2.3Å AUTH S.PERNIGO,A.FUKUZAWA,M.BERTZ,M.HOLT,M.RIEF,R.A.STEINER,AUTH 2 M.GAUTELTITL STRUCTURAL INSIGHT INTO M-BAND ASSEMBLY AND MECHANICS FROMTITL 2 THE TITIN-OBSCURIN-LIKE-1 COMPLEX.REF PROC.NATL.ACAD.SCI.USA V. 107 2908 2010REFN ISSN 0027-8424PMID 20133654DOI 10.1073/PNAS.0913736107 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2i46 ACD crystal structure of human tpp1 2.7Å AUTH F.WANG,E.R.PODELL,A.J.ZAUG,Y.YANG,P.BACIU,T.R.CECH,AUTH 2 M.LEITITL THE POT1-TPP1 TELOMERE COMPLEX IS A TELOMERASETITL 2 PROCESSIVITY FACTOR.REF NATURE V. 445 506 2007REFN ISSN 0028-0836PMID 17237768DOI 10.1038/NATURE05454 Variant Set Distributions Mapped Variants
General Structure Information 2ctt DNAJA3 solution structure of zinc finger domain from human dnaj subfamily a menber 3 -1.0Å AUTH N.KOBAYASHI,N.TOCHIO,K.SAITO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF ZINC FINGER DOMAIN FROMTITL 2 HUMAN DNAJ SUBFAMILY A MENBER 3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3lpw TTN crystal structure of the fniii-tandem a77-a78 from the a-band of titin 1.65Å AUTH R.M.BUCHER,D.I.SVERGUN,C.MUHLE-GOLL,O.MAYANSTITL THE STRUCTURE OF THE FNIII TANDEM A77-A78 POINTS TO ATITL 2 PERIODICALLY CONSERVED ARCHITECTURE IN THE MYOSIN-BINDINGTITL 3 REGION OF TITINREF J.MOL.BIOL. V. 401 843 2010REFN ISSN 0022-2836PMID 20542041DOI 10.1016/J.JMB.2010.06.011 Variant Set Distributions Mapped Variants
General Structure Information 2wh5 ACBD4 crystal structure of human acyl-coa binding domain 4 complexed with stearoyl-coa 2.6Å AUTH N.SHAFQAT,W.W.YUE,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN ACYL-COA BINDING DOMAINTITL 2 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants