Assessment of Structural Intolerance and Durability
General Structure Information 1x3s RAB18 crystal structure of human rab18 in complex with gppnhp 1.32Å AUTH M.KUKIMOTO-NIINO,K.MURAYAMA,L.CHEN,Z.J.LIU,AUTH 2 B.C.WANG,M.SHIROUZU,S.YOKOYAMATITL CRYSTAL STRUCTURE OF HUMAN RAB18 IN COMPLEX WITHTITL 2 GPPNHPREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2kiu FOXP1 solution structure and backbone dynamics of the dna-binding domain of foxp1: insight into its domain swapping -1.0Å AUTH Y.P.CHU,C.H.CHANG,J.H.SHIU,Y.T.CHANG,C.Y.CHEN,W.J.CHUANGTITL SOLUTION STRUCTURE AND BACKBONE DYNAMICS OF THE DNA-BINDINGTITL 2 DOMAIN OF FOXP1: INSIGHT INTO ITS DOMAIN SWAPPING AND DNATITL 3 BINDING.REF PROTEIN SCI. V. 20 908 2011REFN ISSN 0961-8368PMID 21416545DOI 10.1002/PRO.626 […]
General Structure Information 3pnw TDRD3 crystal structure of the tudor domain of human tdrd3 in complex with an anti-tdrd3 fab 2.05Å AUTH H.PERSSON,W.YE,A.WERNIMONT,J.J.ADAMS,A.KOIDE,S.KOIDE,R.LAM,AUTH 2 S.S.SIDHUTITL CDR-H3 DIVERSITY IS NOT REQUIRED FOR ANTIGEN RECOGNITION BYTITL 2 SYNTHETIC ANTIBODIES.REF J.MOL.BIOL. V. 425 803 2013REFN ISSN 0022-2836PMID 23219464DOI 10.1016/J.JMB.2012.11.037 Variant Set Distributions Mapped Variants
General Structure Information 2eeh PDZD7 solution structure of first pdz domain of pdz domain containing protein 7 -1.0Å AUTH T.N.NIRAULA,N.TOCHIO,T.TOMIZAWA,K.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF FIRST PDZ DOMAIN OF PDZTITL 2 DOMAIN CONTAINING PROTEIN 7REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2gwf RNF41 structure of a usp8-nrdp1 complex 2.3Å AUTH G.V.AVVAKUMOV,J.R.WALKER,S.XUE,P.J.FINERTY JR.,F.MACKENZIE,AUTH 2 E.M.NEWMAN,S.DHE-PAGANONTITL AMINO-TERMINAL DIMERIZATION, NRDP1-RHODANESE INTERACTION,TITL 2 AND INHIBITED CATALYTIC DOMAIN CONFORMATION OF THETITL 3 UBIQUITIN-SPECIFIC PROTEASE 8 (USP8).REF J.BIOL.CHEM. V. 281 38061 2006REFN ISSN 0021-9258PMID 17035239DOI 10.1074/JBC.M606704200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2yra SEZ6L solution structure of the zinc finger domains (1-87) from human f-box only protein -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE ZINC FINGER DOMAINSTITL 2 (1-87) FROM HUMAN F-BOX ONLY PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3mop MYD88 the ternary death domain complex of myd88, irak4, and irak2 3.4Å AUTH S.C.LIN,Y.C.LO,H.WUTITL HELICAL ASSEMBLY IN THE MYD88-IRAK4-IRAK2 COMPLEX INTITL 2 TLR/IL-1R SIGNALLING.REF NATURE V. 465 885 2010REFN ISSN 0028-0836PMID 20485341DOI 10.1038/NATURE09121 Variant Set Distributions Mapped Variants
General Structure Information 4h87 SLC4A1AP crystal structure of a fha domain of kanadaptin (slc4a1ap) from homo sapiens at 1.55 a resolution 1.55Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG)TITL CRYSTAL STRUCTURE OF A FHA DOMAIN OF KANADAPTIN (SLC4A1AP)TITL 2 FROM HOMO SAPIENS AT 1.55 A RESOLUTIONREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3fa2 BARD1 crystal structure of the brca1 associated ring domain (bard1) tandem brct domains 2.2Å AUTH D.FOX 3RD,I.LE TRONG,R.E.STENKAMP,R.E.KLEVITTITL CRYSTAL STRUCTURE OF THE BRCA1 ASSOCIATED RING DOMAINTITL 2 (BARD1) TANDEM BRCT DOMAINSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4i1o RAB1B crystal structure of the legionella pneumophila gap domain of lepb in complex with rab1b bound to gdp and bef3 2.7Å AUTH E.MIHAI GAZDAG,A.STRELLER,I.HANEBURGER,H.HILBI,I.R.VETTER,AUTH 2 R.S.GOODY,A.ITZENTITL MECHANISM OF RAB1B DEACTIVATION BY THE LEGIONELLATITL 2 PNEUMOPHILA GAP LEPB.REF EMBO REP. V. 14 199 2013REFN ISSN 1469-221XPMID 23288104DOI 10.1038/EMBOR.2012.211 Variant Set Distributions Ripley’s […]