General Structure Information
| PDB ID | 1x3s |
| HGNC Gene Label(s) | RAB18 |
| Structure Name | crystal structure of human rab18 in complex with gppnhp |
| Resolution | 1.32Å |
| Reference | AUTH M.KUKIMOTO-NIINO,K.MURAYAMA,L.CHEN,Z.J.LIU,AUTH 2 B.C.WANG,M.SHIROUZU,S.YOKOYAMATITL CRYSTAL STRUCTURE OF HUMAN RAB18 IN COMPLEX WITHTITL 2 GPPNHPREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 175 |
| Number Of SNVs | 35 |
| Number Of Permutations | 10577 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.072 |
| p-value | 0.331 |
COSMIC
| Number Of Residues | 175 |
| Number Of SNVs | 3 |
| Number Of Permutations | 46 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.667 |
| p-value | 0.353 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 35 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.57 |
| p-value | 0.475 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
