Assessment of Structural Intolerance and Durability
General Structure Information 3pb9 QPCTL crystal structure of the catalytic domain of human golgi-resident glutaminyl cyclase in complex with 1-benzylimidazole 1.12Å AUTH K.F.HUANG,S.S.LIAW,W.L.HUANG,C.Y.CHIA,Y.C.LO,Y.L.CHEN,AUTH 2 A.H.J.WANGTITL STRUCTURES OF HUMAN GOLGI-RESIDENT GLUTAMINYL CYCLASE ANDTITL 2 ITS COMPLEXES WITH INHIBITORS REVEAL A LARGE LOOP MOVEMENTTITL 3 UPON INHIBITOR BINDINGREF J.BIOL.CHEM. V. 286 12439 2011REFN ISSN 0021-9258PMID 21288892DOI 10.1074/JBC.M110.208595 […]
General Structure Information 3dzx TBC1D22B crystal structure of the rabgap domain of human tbc1d22b 2.3Å AUTH L.NEDYALKOVA,Y.TONG,W.TEMPEL,Y.SHEN,F.MACKENZIE,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,M.WILKSTROM,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE RABGAP DOMAIN OF HUMAN TBC1D22BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4jqf OBFC1 structure of the c-terminal domain of human telomeric stn1 1.6Å AUTH C.BRYAN,C.RICE,M.HARKISHEIMER,D.C.SCHULTZ,E.SKORDALAKESTITL STRUCTURE OF THE HUMAN TELOMERIC STN1-TEN1 CAPPING COMPLEX.REF PLOS ONE V. 8 66756 2013REFN ESSN 1932-6203PMID 23826127DOI 10.1371/JOURNAL.PONE.0066756 Variant Set Distributions Mapped Variants
General Structure Information 2dlv RGS18 solution structure of the rgs domain of human regulator of g-protein signaling 18 -1.0Å AUTH H.P.ZHANG,T.SUETAKE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RGS DOMAIN OF HUMANTITL 2 REGULATOR OF G-PROTEIN SIGNALING 18REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2d9o DNAJC17 solution structure of rna binding domain in hypothetical protein flj10634 -1.0Å AUTH K.TSUDA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN INTITL 2 HYPOTHETICAL PROTEIN FLJ10634REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3zdq ABCB10 structure of the human mitochondrial abc transporter, abcb10 (nucleotide-free form) 2.85Å AUTH C.A.SHINTRE,A.C.W.PIKE,Q.LI,J.KIM,A.J.BARR,S.GOUBIN,AUTH 2 L.SHRESTHA,J.YANG,G.BERRIDGE,J.ROSS,P.J.STANSFELD,AUTH 3 M.S.P.SANSOM,A.M.EDWARDS,C.BOUNTRA,B.D.MARSDEN,F.VON DELFT,AUTH 4 A.N.BULLOCK,O.GILEADI,N.A.BURGESS-BROWN,E.P.CARPENTERTITL STRUCTURES OF ABCB10, A HUMAN ATP-BINDING CASSETTETITL 2 TRANSPORTER IN APO- AND NUCLEOTIDE-BOUND STATESREF PROC.NATL.ACAD.SCI.USA V. 110 9710 2013REFN ISSN 0027-8424PMID 23716676DOI 10.1073/PNAS.1217042110 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 1v95 NCOA5 solution structure of anticodon binding domain from nuclear receptor coactivator 5 (human kiaa1637 protein) -1.0Å AUTH C.ZHAO,T.KIGAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF ANTICODON BINDING DOMAINTITL 2 FROM NUCLEAR RECEPTOR COACTIVATOR 5 (HUMANTITL 3 KIAA1637 PROTEIN)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1x5e TMX1 the solution structure of the thioredoxin-like domain of human thioredoxin-related transmembrane protein -1.0Å AUTH N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL THE SOLUTION STRUCTURE OF THE THIOREDOXIN-LIKETITL 2 DOMAIN OF HUMAN THIOREDOXIN-RELATED TRANSMEMBRANETITL 3 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4l1d SCN3B voltage-gated sodium channel beta3 subunit ig domain 2.5Å AUTH S.NAMADURAI,D.BALASURIYA,R.RAJAPPA,M.WIEMHOFER,K.STOTT,AUTH 2 J.KLINGAUF,J.M.EDWARDSON,D.Y.CHIRGADZE,A.P.JACKSONTITL CRYSTAL STRUCTURE AND MOLECULAR IMAGING OF THE NAV CHANNELTITL 2 BETA 3 SUBUNIT INDICATES A TRIMERIC ASSEMBLY.REF J.BIOL.CHEM. V. 289 10797 2014REFN ISSN 0021-9258PMID 24567321DOI 10.1074/JBC.M113.527994 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2dba UNC45A the solution structure of the tetratrico peptide repeat of human smooth muscle cell associated protein-1, isoform 2 -1.0Å AUTH N.TOCHIO,A.SASAGAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL THE SOLUTION STRUCTURE OF THE TETRATRICO PEPTIDETITL 2 REPEAT OF HUMAN SMOOTH MUSCLE CELL ASSOCIATEDTITL 3 PROTEIN-1, ISOFORM 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants