Assessment of Structural Intolerance and Durability
General Structure Information 2k2o MYOF solution structure of the inner dysf domain of human myoferlin -1.0Å AUTH P.PATEL,R.HARRIS,S.M.GEDDES,E.M.STREHLE,J.D.WATSON,AUTH 2 R.BASHIR,K.BUSHBY,P.C.DRISCOLL,N.H.KEEPTITL SOLUTION STRUCTURE OF THE INNER DYSF DOMAIN OFTITL 2 MYOFERLIN AND IMPLICATIONS FOR LIMB GIRDLETITL 3 MUSCULAR DYSTROPHY TYPE 2B.REF J.MOL.BIOL. V. 379 981 2008REFN ISSN 0022-2836PMID 18495154DOI 10.1016/J.JMB.2008.04.046 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 4doh IL20RA il20/il201/il20r2 ternary complex 2.8Å AUTH N.J.LOGSDON,A.DESHPANDE,B.D.HARRIS,K.R.RAJASHANKAR,AUTH 2 M.R.WALTERTITL STRUCTURAL BASIS FOR RECEPTOR SHARING AND ACTIVATION BYTITL 2 INTERLEUKIN-20 RECEPTOR-2 (IL-20R2) BINDING CYTOKINES.REF PROC.NATL.ACAD.SCI.USA V. 109 12704 2012REFN ISSN 0027-8424PMID 22802649DOI 10.1073/PNAS.1117551109 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4doh IL20 il20/il201/il20r2 ternary complex 2.8Å AUTH N.J.LOGSDON,A.DESHPANDE,B.D.HARRIS,K.R.RAJASHANKAR,AUTH 2 M.R.WALTERTITL STRUCTURAL BASIS FOR RECEPTOR SHARING AND ACTIVATION BYTITL 2 INTERLEUKIN-20 RECEPTOR-2 (IL-20R2) BINDING CYTOKINES.REF PROC.NATL.ACAD.SCI.USA V. 109 12704 2012REFN ISSN 0027-8424PMID 22802649DOI 10.1073/PNAS.1117551109 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3u9j FBXL5 crystal structure of oxidized human fbxl5 hemerythrin like domain 1.6Å AUTH C.SHU,M.W.SUNG,M.D.STEWART,T.I.IGUMENOVA,X.TAN,P.LITITL THE STRUCTURAL BASIS OF IRON SENSING BY THE HUMAN F-BOXTITL 2 PROTEIN FBXL5.REF CHEMBIOCHEM V. 13 788 2012REFN ISSN 1439-4227PMID 22492618DOI 10.1002/CBIC.201200043 Variant Set Distributions Mapped Variants
General Structure Information 2dae TAB2 solution structure of the n-terminal cue domain in the human mitogen-activated protein kinase kinase kinase 7 interacting protein 2 (map3k7ip2) -1.0Å AUTH C.ZHAO,T.KIGAWA,M.SATO,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE N-TERMINAL CUE DOMAIN INTITL 2 THE HUMAN MITOGEN-ACTIVATED PROTEIN KINASE KINASETITL 3 KINASE 7 INTERACTING PROTEIN 2 (MAP3K7IP2)REF TO BE PUBLISHEDREFN Variant Set […]
General Structure Information 3qnt NPC1L1 npc1l1 (ntd) structure 2.83Å AUTH H.J.KWON,M.PALNITKAR,J.DEISENHOFERTITL THE STRUCTURE OF THE NPC1L1 N-TERMINAL DOMAIN IN A CLOSEDTITL 2 CONFORMATION.REF PLOS ONE V. 6 E1872 2011REFN ESSN 1932-6203PMID 21525977DOI 10.1371/JOURNAL.PONE.0018722 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2dmk MID2 the solution structure of the fn3 domain of human midline 2 protein -1.0Å AUTH N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL THE SOLUTION STRUCTURE OF THE FN3 DOMAIN OF HUMANTITL 2 MIDLINE 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1x1f STAP1 solution structure of the ph domain of human docking protein brdg1 -1.0Å AUTH H.LI,T.TOMIZAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PH DOMAIN OF HUMANTITL 2 DOCKING PROTEIN BRDG1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dzr GTF2IRD1 solution structure of rsgi ruh-067, a gtf2i domain in human cdna -1.0Å AUTH Y.DOI-KATAYAMA,H.HIROTA,Y.MUTO,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-067, A GTF2I DOMAINTITL 2 IN HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3toj ASH2L structure of the spry domain of human ash2l 2.07Å AUTH Y.CHEN,F.CAO,B.WAN,Y.DOU,M.LEITITL STRUCTURE OF THE SPRY DOMAIN OF HUMAN ASH2L AND ITSTITL 2 INTERACTIONS WITH RBBP5 AND DPY30.REF CELL RES. V. 22 598 2012REFN ISSN 1001-0602PMID 22231628DOI 10.1038/CR.2012.9 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants