Assessment of Structural Intolerance and Durability
General Structure Information 2keo HERC2 solution nmr structure of human protein hs00059, cytochrome-b5-like domain of the herc2 e3 ligase. northeast structural genomics consortium (nesg) target ht98a -1.0Å AUTH A.LEMAK,A.GUTMANAS,C.FARES,H.QUYANG,Y.LI,G.MONTELIONE,AUTH 2 C.ARROWSMITH,S.DHE-PAGANONTITL SOLUTION NMR STRUCTURE OF HUMAN PROTEIN HS00059REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2kl7 EFEMP2 solution nmr structure of the egf-like 1 domain of human fibulin-4. northeast structural genomics target hr6275 -1.0Å AUTH P.ROSSI,Y.CHIANG,S.ANDERSON,G.T.MONTELIONETITL SOLUTION NMR STRUCTURE OF THE EGF-LIKE 1 DOMAIN OFTITL 2 HUMAN FIBULIN-4. NORTHEAST STRUCTURAL GENOMICSTITL 3 TARGET HR6275REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3lrq TRIM37 crystal structure of the u-box domain of human ubiquitin- protein ligase (e3), northeast structural genomics consortium target hr4604d. 2.29Å AUTH A.KUZIN,Y.CHEN,J.SEETHARAMAN,M.MAO,R.XIAO,AUTH 2 C.CICCOSANTI,R.SHASTRY,J.K.EVERETT,R.NAIR,AUTH 3 T.B.ACTON,B.ROST,G.T.MONTELIONE,L.TONG,J.F.HUNTTITL E3 UBIQUITIN-PROTEIN LIGASE RING DOMAIN FROM HUMANTITL 2 TRIPARTITE MOTIF-CONTAINING PROTEIN 37 (TRIM37),TITL 3 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGETTITL 4 HR4604D.REF TO BE PUBLISHEDREFN Variant […]
General Structure Information 2lvc OBSL1 solution nmr structure of ig like domain (805-892) of obscurin-like protein 1 from homo sapiens, northeast structural genomics consortium (nesg) target hr8578k -1.0Å AUTH S.PULAVARTI,A.ELETSKY,D.K.SUKUMARAN,D.LEE,E.KOHAN,H.JANJUA,AUTH 2 R.XIAO,T.B.ACTON,J.K.EVERETT,K.PEDERSON,J.PRESTEGARD,AUTH 3 G.T.MONTELIONE,T.SZYPERSKITITL SOLUTION NMR STRUCTURE OF IG LIKE DOMAIN (805-892) OFTITL 2 OBSCURIN-LIKE PROTEIN 1 FROM HOMO SAPIENS, NORTHEASTTITL 3 STRUCTURAL GENOMICS CONSORTIUM […]
General Structure Information 2gow UBL3 solution structure of bc059385 from homo sapiens -1.0Å AUTH N.B.DE LA CRUZ,F.C.PETERSON,B.L.LYTLE,B.F.VOLKMANTITL SOLUTION STRUCTURE OF A MEMBRANE-ANCHOREDTITL 2 UBIQUITIN-FOLD (MUB) PROTEIN FROM HOMO SAPIENS.REF PROTEIN SCI. V. 16 1479 2007REFN ISSN 0961-8368PMID 17567738DOI 10.1110/PS.072834007 Variant Set Distributions Mapped Variants
General Structure Information 2qs9 RBBP9 crystal structure of the human retinoblastoma-binding protein 9 (rbbp-9). nesg target hr2978 1.72Å AUTH S.M.VOROBIEV,M.SU,J.SEETHARAMAN,Y.J.HUANG,C.X.CHEN,AUTH 2 M.MAGLAQUI,H.JANJUA,M.PROUDFOOT,A.YAKUNIN,R.XIAO,AUTH 3 T.B.ACTON,G.T.MONTELIONE,L.TONGTITL CRYSTAL STRUCTURE OF HUMAN RETINOBLASTOMA BINDINGTITL 2 PROTEIN 9.REF PROTEINS V. 74 526 2008REFN ISSN 0887-3585PMID 19004028DOI 10.1002/PROT.22278 Variant Set Distributions Mapped Variants
General Structure Information 2p8e PPM1B crystal structure of the serine/threonine phosphatase domain of human ppm1b 1.82Å AUTH S.C.ALMO,J.B.BONANNO,J.M.SAUDER,S.EMTAGE,AUTH 2 T.P.DILORENZO,V.MALASHKEVICH,S.R.WASSERMAN,AUTH 3 S.SWAMINATHAN,S.ESWARAMOORTHY,R.AGARWAL,D.KUMARAN,AUTH 4 M.MADEGOWDA,S.RAGUMANI,Y.PATSKOVSKY,J.ALVARADO,AUTH 5 U.A.RAMAGOPAL,J.FABER-BARATA,M.R.CHANCE,A.SALI,AUTH 6 A.FISER,Z.Y.ZHANG,D.S.LAWRENCE,S.K.BURLEYTITL STRUCTURAL GENOMICS OF PROTEIN PHOSPHATASES.REF J.STRUCT.FUNCT.GENOM. V. 8 121 2007REFN ISSN 1345-711XPMID 18058037DOI 10.1007/S10969-007-9036-1 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2q53 GGCT ensemble refinement of the crystal structure of uncharacterized protein loc79017 from homo sapiens 2.01Å AUTH E.BAE,C.A.BINGMAN,D.J.ACETI,G.N.PHILLIPS JR.TITL CRYSTAL STRUCTURE OF HOMO SAPIENS PROTEIN LOC79017.REF PROTEINS V. 70 588 2008REFN ISSN 0887-3585PMID 17932939DOI 10.1002/PROT.21719 Variant Set Distributions Mapped Variants
General Structure Information 2lx7 GAS7 solution nmr structure of sh3 domain of growth arrest-specific protein 7 (gas7) (fragment 1-60) from homo sapiens, northeast structural genomics consortium (nesg) target hr8574a -1.0Å AUTH Y.YANG,T.A.RAMELOT,L.DAN,E.KOHAN,H.JANJUA,R.XIAO,T.ACTON,AUTH 2 J.K.EVERETT,G.T.MONTELIONE,M.A.KENNEDYTITL SOLUTION NMR STRUCTURE OF SH3 DOMAIN OF GROWTHTITL 2 ARREST-SPECIFIC PROTEIN 7 (GAS7) (FRAGMENT 1-60) FROM HOMOTITL 3 SAPIENS, NORTHEAST STRUCTURAL […]
General Structure Information 2q5e CTDSP2 crystal structure of human carboxy-terminal domain rna polymerase ii polypeptide a small phosphatase 2 2.51Å AUTH S.C.ALMO,J.B.BONANNO,J.M.SAUDER,S.EMTAGE,AUTH 2 T.P.DILORENZO,V.MALASHKEVICH,S.R.WASSERMAN,AUTH 3 S.SWAMINATHAN,S.ESWARAMOORTHY,R.AGARWAL,D.KUMARAN,AUTH 4 M.MADEGOWDA,S.RAGUMANI,Y.PATSKOVSKY,J.ALVARADO,AUTH 5 U.A.RAMAGOPAL,J.FABER-BARATA,M.R.CHANCE,A.SALI,AUTH 6 A.FISER,Z.Y.ZHANG,D.S.LAWRENCE,S.K.BURLEYTITL STRUCTURAL GENOMICS OF PROTEIN PHOSPHATASES.REF J.STRUCT.FUNCT.GENOM. V. 8 121 2007REFN ISSN 1345-711XPMID 18058037DOI 10.1007/S10969-007-9036-1 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]