Assessment of Structural Intolerance and Durability
General Structure Information 3k0w MALT1 crystal structure of the tandem ig-like c2-type 2 domains of the human mucosa-associated lymphoid tissue lymphoma translocation protein 1 2.8Å AUTH J.R.WALKER,L.QIU,C.BUTLER-COLE,C.BOUNTRA,J.WEIGELT,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 S.DHE-PAGANONTITL STRUCTURE OF THE TANDEM IG-LIKE C2-TYPE 2 DOMAINSTITL 2 OF THE HUMAN MUCOSA-ASSOCIATED LYMPHOID TISSUETITL 3 LYMPHOMA TRANSLOCATION PROTEIN 1.REF TO BE PUBLISHEDREFN Variant […]
General Structure Information 3g5c ADAM22 structural and biochemical studies on the ectodomain of human adam22 2.36Å AUTH H.LIU,A.SHIM,X.CHEN,X.HETITL STRUCTURAL AND BIOCHEMICAL STUDIES ON THE ECTODOMAIN OFTITL 2 HUMAN ADAM22REF J.BIOL.CHEM. 2009REFN ESSN 1083-351X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3haj PACSIN2 crystal structure of human pacsin2 f-bar domain (p212121 lattice) 2.78Å AUTH Q.WANG,M.V.NAVARRO,G.PENG,E.MOLINELLI,S.LIN GOH,AUTH 2 B.L.JUDSON,K.R.RAJASHANKAR,H.SONDERMANNTITL MOLECULAR MECHANISM OF MEMBRANE CONSTRICTION ANDTITL 2 TUBULATION MEDIATED BY THE F-BAR PROTEINTITL 3 PACSIN/SYNDAPIN.REF PROC.NATL.ACAD.SCI.USA V. 106 12700 2009REFN ISSN 0027-8424PMID 19549836DOI 10.1073/PNAS.0902974106 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 2k2o MYOF solution structure of the inner dysf domain of human myoferlin -1.0Å AUTH P.PATEL,R.HARRIS,S.M.GEDDES,E.M.STREHLE,J.D.WATSON,AUTH 2 R.BASHIR,K.BUSHBY,P.C.DRISCOLL,N.H.KEEPTITL SOLUTION STRUCTURE OF THE INNER DYSF DOMAIN OFTITL 2 MYOFERLIN AND IMPLICATIONS FOR LIMB GIRDLETITL 3 MUSCULAR DYSTROPHY TYPE 2B.REF J.MOL.BIOL. V. 379 981 2008REFN ISSN 0022-2836PMID 18495154DOI 10.1016/J.JMB.2008.04.046 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3maz STAP1 crystal structure of the human brdg1/stap-1 sh2 domain in complex with the ntal ptyr136 peptide 1.9Å AUTH T.KANEKO,H.HUANG,B.ZHAO,L.LI,H.LIU,C.K.VOSS,C.WU,AUTH 2 M.R.SCHILLER,S.S.LITITL LOOPS GOVERN SH2 DOMAIN SPECIFICITY BY CONTROLLING ACCESSTITL 2 TO BINDING POCKETS.REF SCI.SIGNAL. V. 3 RA34 2010REFN ESSN 1937-9145PMID 20442417DOI 10.1126/SCISIGNAL.2000796 Variant Set Distributions Mapped Variants
General Structure Information 3krm IGF2BP1 imp1 kh34 2.75Å AUTH J.A.CHAO,Y.PATSKOVSKY,V.PATEL,M.LEVY,S.C.ALMO,AUTH 2 R.H.SINGERTITL ZBP1 RECOGNITION OF BETA-ACTIN ZIPCODE INDUCES RNATITL 2 LOOPING.REF GENES DEV. V. 24 148 2010REFN ISSN 0890-9369PMID 20080952DOI 10.1101/GAD.1862910 Variant Set Distributions Mapped Variants
General Structure Information 2wfd LARS structure of the human cytosolic leucyl-trna synthetase editing domain 3.25Å AUTH E.SEIRADAKE,W.MAO,V.HERNANDEZ,S.J.BAKER,AUTH 2 J.J.PLATTNER,M.R.K.ALLEY,S.CUSACKTITL CRYSTAL STRUCTURES OF THE HUMAN AND FUNGALTITL 2 CYTOSOLIC LEUCYL-TRNA SYNTHETASE EDITING DOMAINS:TITL 3 A STRUCTURAL BASIS FOR THE RATIONAL DESIGN OFTITL 4 ANTIFUNGAL BENZOXABOROLES.REF J.MOL.BIOL. V. 390 196 2009REFN ISSN 0022-2836PMID 19426743DOI 10.1016/J.JMB.2009.04.073 Variant Set […]
General Structure Information 3in5 POLK structure of human dna polymerase kappa inserting datp opposite an 8-oxog dna lesion 3.2Å AUTH R.VASQUEZ-DEL CARPIO,T.D.SILVERSTEIN,S.LONE,AUTH 2 M.K.SWAN,J.R.CHOUDHURY,R.E.JOHNSON,S.PRAKASH,AUTH 3 L.PRAKASH,A.K.AGGARWALTITL STRUCTURE OF HUMAN DNA POLYMERASE KAPPA INSERTINGTITL 2 DATP OPPOSITE AN 8-OXOG DNA LESIONREF PLOS ONE V. 4 E5766 2009REFN ESSN 1932-6203PMID 19492058DOI 10.1371/JOURNAL.PONE.0005766 Variant Set Distributions Pathogenic Proximity […]
General Structure Information 2xd7 H2AFY2 crystal structure of the macro domain of human core histone h2a 2.09Å AUTH M.VOLLMAR,C.PHILLIPPS,E.P.CARPENTER,J.R.C.MUNIZ,AUTH 2 T.KROJER,E.UGOCHUKWU,F.VON DELFT,C.BOUNTRA,AUTH 3 C.H.ARROWSMITH,J.WEIGELT,A.EDWARDS,O.GILEADITITL CRYSTAL STRUCTURE OF THE MACRO DOMAIN OF HUMANTITL 2 CORE HISTONE H2AREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3l82 FBXO4 x-ray crystal structure of trf1 and fbx4 complex 2.4Å AUTH Z.ZENG,W.WANG,Y.YANG,Y.CHEN,X.YANG,J.A.DIEHL,X.LIU,M.LEITITL STRUCTURAL BASIS OF SELECTIVE UBIQUITINATION OF TRF1 BYTITL 2 SCF(FBX4)REF DEV.CELL V. 18 214 2010REFN ISSN 1534-5807PMID 20159592DOI 10.1016/J.DEVCEL.2010.01.007 Variant Set Distributions Mapped Variants