Assessment of Structural Intolerance and Durability
General Structure Information 3cok PLK4 crystal structure of plk4 kinase 2.25Å AUTH S.ATWELL,S.K.BURLEY,A.HOULE,B.LEON,L.A.PELLETIER,AUTH 2 J.M.SAUDERTITL CRYSTAL STRUCTURE OF PLK4 KINASE.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3h11 CFLAR zymogen caspase-8:c-flipl protease domain complex 1.9Å AUTH J.W.YU,P.D.JEFFREY,Y.SHITITL MECHANISM OF PROCASPASE-8 ACTIVATION BY C-FLIPL.REF PROC.NATL.ACAD.SCI.USA V. 106 8169 2009REFN ISSN 0027-8424PMID 19416807DOI 10.1073/PNAS.0812453106 Variant Set Distributions Mapped Variants
General Structure Information 3fdl BCL2L11 bim bh3 peptide in complex with bcl-xl 1.78Å AUTH E.F.LEE,J.D.SADOWSKY,B.J.SMITH,P.E.CZABOTAR,AUTH 2 K.J.PETERSON-KAUFMAN,P.M.COLMAN,S.H.GELLMAN,AUTH 3 W.D.FAIRLIETITL HIGH-RESOLUTION STRUCTURAL CHARACTERIZATION OF ATITL 2 HELICAL ALPHA/BETA-PEPTIDE FOLDAMER BOUND TO THETITL 3 ANTI-APOPTOTIC PROTEIN BCL-X(L)REF ANGEW.CHEM.INT.ED.ENGL. V. 48 4318 2009REFN ISSN 1433-7851PMID 19229915DOI 10.1002/ANIE.200805761 Variant Set Distributions Mapped Variants