General Structure Information
| PDB ID | 3cok |
| HGNC Gene Label(s) | PLK4 |
| Structure Name | crystal structure of plk4 kinase |
| Resolution | 2.25Å |
| Reference | AUTH S.ATWELL,S.K.BURLEY,A.HOULE,B.LEON,L.A.PELLETIER,AUTH 2 J.M.SAUDERTITL CRYSTAL STRUCTURE OF PLK4 KINASE.REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 232 |
| Number Of SNVs | 52 |
| Number Of Permutations | 6675 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.165 |
| p-value | 0.15 |
COSMIC
| Number Of Residues | 232 |
| Number Of SNVs | 3 |
| Number Of Permutations | 77 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 52 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | -0.256 |
| p-value | 0.603 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
