Assessment of Structural Intolerance and Durability
General Structure Information 1u5d SKAP1 crystal structure of the ph domain of skap55 1.7Å AUTH Y.TANG,K.D.SWANSON,B.G.NEEL,M.J.ECKTITL STRUCTURAL BASIS FOR THE DIMERIZATION ANDTITL 2 PHOSPHOINOSITIDE SPECIFICITY OF THE SRCTITL 3 KINASE-ASSOCIATED PHOSPHOPROTEINS SKAP55 ANDTITL 4 SKAP-HOMREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3u1k PNPT1 crystal structure of human pnpase 2.13Å AUTH C.L.LIN,Y.-T.WANG,W.-Z.YANG,Y.-Y.HSIAO,H.S.YUANTITL CRYSTAL STRUCTURE OF HUMAN POLYNUCLEOTIDE PHOSPHORYLASE:TITL 2 INSIGHTS INTO ITS DOMAIN FUNCTION IN RNA BINDING ANDTITL 3 DEGRADATIONREF NUCLEIC ACIDS RES. V. 40 4146 2012REFN ISSN 0305-1048PMID 22210891DOI 10.1093/NAR/GKR1281 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2cof AFAP1L2 solution structure of the c-terminal ph domain of hypothetical protein kiaa1914 from human -1.0Å AUTH H.LI,K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C-TERMINAL PH DOMAIN OFTITL 2 HYPOTHETICAL PROTEIN KIAA1914 FROM HUMANREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2coc FGD3 solution structure of the c-terminal ph domain of fyve, rhogef and ph domain containing protein 3 (fgd3) from human -1.0Å AUTH H.LI,T.TOMIZAWA,N.TOCHIO,Y.MUTO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C-TERMINAL PH DOMAIN OFTITL 2 FYVE, RHOGEF AND PH DOMAIN CONTAINING PROTEIN 3TITL 3 (FGD3) FROM HUMANREF TO BE PUBLISHEDREFN Variant Set […]
General Structure Information 3mpx FGD5 crystal structure of the dh and ph-1 domains of human fgd5 2.8Å AUTH Y.SHEN,L.NEDYALKOVA,Y.TONG,W.TEMPEL,L.CROMBET,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,AUTH 3 H.PARKTITL CRYSTAL STRUCTURE OF THE DH AND PH-1 DOMAINS OF HUMAN FGD5REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3pp2 ARHGAP27 crystal structure of the pleckstrin homology domain of arhgap27 1.42Å AUTH L.SHEN,W.TEMPEL,Y.TONG,L.NEDYALKOVA,Y.LI,A.K.WERNIMONT,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,H.PARKTITL CRYSTAL STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN OFTITL 2 ARHGAP27REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1bwn BTK ph domain and btk motif from brutons tyrosine kinase mutant e41k in complex with ins(1,3,4,5)p4 2.1Å AUTH E.BARALDI,K.D.CARUGO,M.HYVONEN,P.L.SURDO,A.M.RILEY,AUTH 2 B.V.POTTER,R.OBRIEN,J.E.LADBURY,M.SARASTETITL STRUCTURE OF THE PH DOMAIN FROM BRUTONS TYROSINE KINASE INTITL 2 COMPLEX WITH INOSITOL 1,3,4,5-TETRAKISPHOSPHATE.REF STRUCTURE FOLD.DES. V. 7 449 1999REFN ISSN 0969-2126PMID 10196129DOI 10.1016/S0969-2126(99)80057-4 Variant Set Distributions Ripley’s K […]
General Structure Information 1bwn BTK ph domain and btk motif from brutons tyrosine kinase mutant e41k in complex with ins(1,3,4,5)p4 2.1Å AUTH E.BARALDI,K.D.CARUGO,M.HYVONEN,P.L.SURDO,A.M.RILEY,AUTH 2 B.V.POTTER,R.OBRIEN,J.E.LADBURY,M.SARASTETITL STRUCTURE OF THE PH DOMAIN FROM BRUTONS TYROSINE KINASE INTITL 2 COMPLEX WITH INOSITOL 1,3,4,5-TETRAKISPHOSPHATE.REF STRUCTURE FOLD.DES. V. 7 449 1999REFN ISSN 0969-2126PMID 10196129DOI 10.1016/S0969-2126(99)80057-4 Variant Set Distributions Ripley’s K […]
General Structure Information 1bwn BTK ph domain and btk motif from brutons tyrosine kinase mutant e41k in complex with ins(1,3,4,5)p4 2.1Å AUTH E.BARALDI,K.D.CARUGO,M.HYVONEN,P.L.SURDO,A.M.RILEY,AUTH 2 B.V.POTTER,R.OBRIEN,J.E.LADBURY,M.SARASTETITL STRUCTURE OF THE PH DOMAIN FROM BRUTONS TYROSINE KINASE INTITL 2 COMPLEX WITH INOSITOL 1,3,4,5-TETRAKISPHOSPHATE.REF STRUCTURE FOLD.DES. V. 7 449 1999REFN ISSN 0969-2126PMID 10196129DOI 10.1016/S0969-2126(99)80057-4 Variant Set Distributions Ripley’s K […]
General Structure Information 4gnk PLCB3 crystal structure of galphaq in complex with full-length human plcbeta3 4.0Å AUTH A.M.LYON,S.DUTTA,C.A.BOGUTH,G.SKINIOTIS,J.J.TESMERTITL FULL-LENGTH G ALPHA (Q)-PHOSPHOLIPASE C-BETA 3 STRUCTURETITL 2 REVEALS INTERFACES OF THE C-TERMINAL COILED-COIL DOMAIN.REF NAT.STRUCT.MOL.BIOL. V. 20 355 2013REFN ISSN 1545-9993PMID 23377541DOI 10.1038/NSMB.2497 Variant Set Distributions Mapped Variants