General Structure Information
| PDB ID | 3mpx |
| HGNC Gene Label(s) | FGD5 |
| Structure Name | crystal structure of the dh and ph-1 domains of human fgd5 |
| Resolution | 2.8Å |
| Reference | AUTH Y.SHEN,L.NEDYALKOVA,Y.TONG,W.TEMPEL,L.CROMBET,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,AUTH 3 H.PARKTITL CRYSTAL STRUCTURE OF THE DH AND PH-1 DOMAINS OF HUMAN FGD5REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 295 |
| Number Of SNVs | 76 |
| Number Of Permutations | 49813 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.102 |
| p-value | 0.977 |
COSMIC
| Number Of Residues | 295 |
| Number Of SNVs | 3 |
| Number Of Permutations | 27 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 76 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 35.0 |
| K Statistic | -0.355 |
| p-value | 0.378 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
