Assessment of Structural Intolerance and Durability
General Structure Information 4gnk PLCB3 crystal structure of galphaq in complex with full-length human plcbeta3 4.0Å AUTH A.M.LYON,S.DUTTA,C.A.BOGUTH,G.SKINIOTIS,J.J.TESMERTITL FULL-LENGTH G ALPHA (Q)-PHOSPHOLIPASE C-BETA 3 STRUCTURETITL 2 REVEALS INTERFACES OF THE C-TERMINAL COILED-COIL DOMAIN.REF NAT.STRUCT.MOL.BIOL. V. 20 355 2013REFN ISSN 1545-9993PMID 23377541DOI 10.1038/NSMB.2497 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2kie OCRL a ph domain within ocrl bridges clathrin mediated membrane trafficking to phosphoinositide metabolis -1.0Å AUTH Y.MAO,D.M.BALKIN,R.ZONCU,K.S.ERDMANN,L.TOMASINI,AUTH 2 F.HU,M.M.JIN,M.E.HODSDON,P.DE CAMILLITITL A PH DOMAIN WITHIN OCRL BRIDGES CLATHRIN-MEDIATEDTITL 2 MEMBRANE TRAFFICKING TO PHOSPHOINOSITIDE METABOLISMREF EMBO J. V. 28 1831 2009REFN ISSN 0261-4189PMID 19536138DOI 10.1038/EMBOJ.2009.155 Variant Set Distributions Mapped Variants
General Structure Information 4ifs SSRP1 crystal structure of the hssrp1 middle domain 1.93Å AUTH W.J.ZHANG,F.X.ZENG,C.SHAO,Y.W.LIU,L.W.NIU,X.LI,M.K.TENGTITL CRYSTAL STRUCTURE OF THE HSSRP1 MIDDLE DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4k2p TIAM1 the structure of a quintuple mutant of the tiam1 ph-cc-ex domain 1.98Å AUTH M.JOSHI,L.GAKHAR,E.J.FUENTESTITL HIGH-RESOLUTION STRUCTURE OF THE TIAM1 PHN-CC-EX DOMAIN.REF ACTA CRYSTALLOGR.,SECT.F V. 69 744 2013REFN ESSN 1744-3091PMID 23832200DOI 10.1107/S1744309113014206 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3hk0 GRB10 crystal structure of the ra and ph domains of grb10 2.6Å AUTH R.S.DEPETRIS,J.WU,S.R.HUBBARDTITL STRUCTURAL AND FUNCTIONAL STUDIES OF THE RAS-ASSOCIATING ANDTITL 2 PLECKSTRIN-HOMOLOGY DOMAINS OF GRB10 AND GRB14.REF NAT.STRUCT.MOL.BIOL. V. 16 833 2009REFN ISSN 1545-9993PMID 19648926DOI 10.1038/NSMB.1642 Variant Set Distributions Mapped Variants
General Structure Information 2kie OCRL a ph domain within ocrl bridges clathrin mediated membrane trafficking to phosphoinositide metabolis -1.0Å AUTH Y.MAO,D.M.BALKIN,R.ZONCU,K.S.ERDMANN,L.TOMASINI,AUTH 2 F.HU,M.M.JIN,M.E.HODSDON,P.DE CAMILLITITL A PH DOMAIN WITHIN OCRL BRIDGES CLATHRIN-MEDIATEDTITL 2 MEMBRANE TRAFFICKING TO PHOSPHOINOSITIDE METABOLISMREF EMBO J. V. 28 1831 2009REFN ISSN 0261-4189PMID 19536138DOI 10.1038/EMBOJ.2009.155 Variant Set Distributions Mapped Variants
General Structure Information 4ifs SSRP1 crystal structure of the hssrp1 middle domain 1.93Å AUTH W.J.ZHANG,F.X.ZENG,C.SHAO,Y.W.LIU,L.W.NIU,X.LI,M.K.TENGTITL CRYSTAL STRUCTURE OF THE HSSRP1 MIDDLE DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4k2p TIAM1 the structure of a quintuple mutant of the tiam1 ph-cc-ex domain 1.98Å AUTH M.JOSHI,L.GAKHAR,E.J.FUENTESTITL HIGH-RESOLUTION STRUCTURE OF THE TIAM1 PHN-CC-EX DOMAIN.REF ACTA CRYSTALLOGR.,SECT.F V. 69 744 2013REFN ESSN 1744-3091PMID 23832200DOI 10.1107/S1744309113014206 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3hk0 GRB10 crystal structure of the ra and ph domains of grb10 2.6Å AUTH R.S.DEPETRIS,J.WU,S.R.HUBBARDTITL STRUCTURAL AND FUNCTIONAL STUDIES OF THE RAS-ASSOCIATING ANDTITL 2 PLECKSTRIN-HOMOLOGY DOMAINS OF GRB10 AND GRB14.REF NAT.STRUCT.MOL.BIOL. V. 16 833 2009REFN ISSN 1545-9993PMID 19648926DOI 10.1038/NSMB.1642 Variant Set Distributions Mapped Variants
General Structure Information 2ys1 DNM2 solution structure of the ph domain of dynamin-2 from human -1.0Å AUTH H.LI,M.SATO,N.TOCHIO,S.KOSHIBA,S.WATANABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PH DOMAIN OF DYNAMIN-2TITL 2 FROM HUMANREF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants