General Structure Information
| PDB ID | 4k2p |
| HGNC Gene Label(s) | TIAM1 |
| Structure Name | the structure of a quintuple mutant of the tiam1 ph-cc-ex domain |
| Resolution | 1.98Å |
| Reference | AUTH M.JOSHI,L.GAKHAR,E.J.FUENTESTITL HIGH-RESOLUTION STRUCTURE OF THE TIAM1 PHN-CC-EX DOMAIN.REF ACTA CRYSTALLOGR.,SECT.F V. 69 744 2013REFN ESSN 1744-3091PMID 23832200DOI 10.1107/S1744309113014206 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 238 |
| Number Of SNVs | 51 |
| Number Of Permutations | 16083 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.047 |
| p-value | 0.875 |
COSMIC
| Number Of Residues | 238 |
| Number Of SNVs | 5 |
| Number Of Permutations | 188 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.1 |
| p-value | 0.318 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 51 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.574 |
| p-value | 0.029 |