Assessment of Structural Intolerance and Durability
General Structure Information 3voq MAPKAP1 crystal structure of the pleckstrin homology domain of human sin1, a torc2 subunit 2.0Å AUTH D.PAN,Y.MATSUURATITL STRUCTURES OF THE PLECKSTRIN HOMOLOGY DOMAIN OFTITL 2 SACCHAROMYCES CEREVISIAE AVO1 AND ITS HUMAN ORTHOLOGUE SIN1,TITL 3 AN ESSENTIAL SUBUNIT OF TOR COMPLEX 2REF ACTA CRYSTALLOGR.,SECT.F V. 68 386 2012REFN ESSN 1744-3091PMID 22505404DOI 10.1107/S1744309112007178 […]
General Structure Information 2coa PRKD2 solution structure of the ph domain of protein kinase c, d2 type from human -1.0Å AUTH H.LI,K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PH DOMAIN OF PROTEINTITL 2 KINASE C, D2 TYPE FROM HUMANREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2rrf ZFYVE21 the solution structure of the c-terminal region of zinc finger fyve domain-containing protein 21 -1.0Å AUTH M.NAGANO,D.HOSHINO,S.KOSHIBA,T.SHUO,N.KOSHIKAWA,T.TOMIZAWA,AUTH 2 F.HAYASHI,N.TOCHIO,T.HARADA,T.AKIZAWA,S.WATANABE,N.HANDA,AUTH 3 M.SHIROUZU,T.KIGAWA,S.YOKOYAMA,M.SEIKITITL ZF21 PROTEIN, A REGULATOR OF THE DISASSEMBLY OF FOCALTITL 2 ADHESIONS AND CANCER METASTASIS, CONTAINS A NOVELTITL 3 NONCANONICAL PLECKSTRIN HOMOLOGY DOMAINREF J.BIOL.CHEM. V. 286 31598 2011REFN ISSN 0021-9258PMID […]
General Structure Information 2rlo AGAP2 split ph domain of pi3-kinase enhancer -1.0Å AUTH J.YAN,W.WEN,L.N.CHAN,M.ZHANGTITL SPLIT PLECKSTRIN HOMOLOGY DOMAIN-MEDIATEDTITL 2 CYTOPLASMIC-NUCLEAR LOCALIZATION OF PI3-KINASETITL 3 ENHANCER GTPASEREF J.MOL.BIOL. V. 378 425 2008REFN ISSN 0022-2836PMID 18371979DOI 10.1016/J.JMB.2008.02.052 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2d9x OSBPL11 solution structure of the ph domain of oxysterol binding protein-related protein 11 from human -1.0Å AUTH H.LI,M.SATO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PH DOMAIN OF OXYSTEROLTITL 2 BINDING PROTEIN-RELATED PROTEIN 11 FROM HUMANREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3a98 DOCK2 crystal structure of the complex of the interacting regions of dock2 and elmo1 2.1Å AUTH K.HANAWA-SUETSUGU,M.KUKIMOTO-NIINO,C.MISHIMA-TSUMAGARI,AUTH 2 R.AKASAKA,N.OHSAWA,S.SEKINE,T.ITO,N.TOCHIO,S.KOSHIBA,AUTH 3 T.KIGAWA,T.TERADA,M.SHIROUZU,D.KOHDA,A.NISHIKIMI,Y.FUKUI,AUTH 4 S.YOKOYAMATITL STRUCTURAL BASIS OF FUNCTIONAL COMPLEX FORMATION BETWEENTITL 2 DOCK2 AND ELMO1 FOR RAC ACTIVATION IN LYMPHOCYTE CHEMOTAXISREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3a98 ELMO1 crystal structure of the complex of the interacting regions of dock2 and elmo1 2.1Å AUTH K.HANAWA-SUETSUGU,M.KUKIMOTO-NIINO,C.MISHIMA-TSUMAGARI,AUTH 2 R.AKASAKA,N.OHSAWA,S.SEKINE,T.ITO,N.TOCHIO,S.KOSHIBA,AUTH 3 T.KIGAWA,T.TERADA,M.SHIROUZU,D.KOHDA,A.NISHIKIMI,Y.FUKUI,AUTH 4 S.YOKOYAMATITL STRUCTURAL BASIS OF FUNCTIONAL COMPLEX FORMATION BETWEENTITL 2 DOCK2 AND ELMO1 FOR RAC ACTIVATION IN LYMPHOCYTE CHEMOTAXISREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3odx ARHGEF1 crystal structure of an n-terminally truncated linker-dh/ph domains of p115-rhogef 3.2Å AUTH Z.CHEN,L.GUO,S.R.SPRANG,P.C.STERNWEISTITL MODULATION OF A GEF SWITCH: AUTOINHIBITION OF THE INTRINSICTITL 2 GUANINE NUCLEOTIDE EXCHANGE ACTIVITY OF P115-RHOREFREF PROTEIN SCI. V. 20 107 2011REFN ISSN 0961-8368 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2cod ARAP2 solution structure of the n-terminal ph domain of arap2 protein from human -1.0Å AUTH H.LI,T.TOMIZAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE N-TERMINAL PH DOMAIN OFTITL 2 ARAP2 PROTEIN FROM HUMANREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1mi1 NBEA crystal structure of the ph-beach domain of human neurobeachin 2.9Å AUTH G.JOGL,Y.SHEN,D.GEBAUER,J.LI,K.WIEGMANN,H.KASHKAR,AUTH 2 M.KRONKE,L.TONGTITL CRYSTAL STRUCTURE OF THE BEACH DOMAIN REVEALS ANTITL 2 UNUSUAL FOLD AND EXTENSIVE ASSOCIATION WITH ATITL 3 NOVEL PH DOMAIN.REF EMBO J. V. 21 4785 2002REFN ISSN 0261-4189PMID 12234919DOI 10.1093/EMBOJ/CDF502 Variant Set Distributions Ripley’s K Analysis […]