3VOQ.A | MAPKAP1

PDB ID	3voq
HGNC Gene Label(s)	MAPKAP1
Structure Name	crystal structure of the pleckstrin homology domain of human sin1, a torc2 subunit
Resolution	2.0Å
Reference	AUTH D.PAN,Y.MATSUURATITL STRUCTURES OF THE PLECKSTRIN HOMOLOGY DOMAIN OFTITL 2 SACCHAROMYCES CEREVISIAE AVO1 AND ITS HUMAN ORTHOLOGUE SIN1,TITL 3 AN ESSENTIAL SUBUNIT OF TOR COMPLEX 2REF ACTA CRYSTALLOGR.,SECT.F V. 68 386 2012REFN ESSN 1744-3091PMID 22505404DOI 10.1107/S1744309112007178

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
9:128246737		T>A	A:398	(22.72, -12.94, -2.90)
9:128246731		V>I	A:400	(17.51, -16.01, -4.32)
9:128230385		I>T	A:404	(6.30, -19.55, -1.25)
9:128230359		P>A	A:413	(21.11, -20.40, -4.69)
9:128230322		I>S	A:425	(31.34, -17.58, 1.22)
9:128230302		I>V	A:432	(11.57, -23.55, 5.86)
9:128230293		D>N	A:435	(4.09, -25.99, 10.29)
9:128230284		C>R	A:438	(6.73, -17.52, 12.95)
9:128230261	rs566104427	E>D	A:445	(8.05, 0.53, 1.40)
9:128230251	rs546168424	S>G	A:449	(12.42, -0.07, -6.28)
9:128206872	rs117468097	A>T	A:451	(11.58, -3.50, -0.36)
9:128206869		I>V	A:452	(13.37, -4.81, 3.07)
9:128206856	COSM1105190 COSM1187814	T>M	A:456	(10.66, -15.35, 11.45)
9:128206844		N>S	A:460	(17.42, -26.78, 16.42)
9:128206809	COSM3904091 COSM3904090	A>T	A:472	(7.12, -3.23, -3.53)
9:128206800	rs149285651	V>I	A:475	(7.56, -7.40, -1.03)
9:128206796	rs555771876	N>S	A:476	(3.53, -6.04, -0.75)
9:128201272		S>L	A:488	(-4.61, -21.19, 7.64)
9:128201269		R>Q	A:489	(-1.09, -21.96, 11.20)

3VOQ.A | MAPKAP1.