General Structure Information 2rmn TP63 the solution structure of the p63 dna-binding domain -1.0Å AUTH A.ENTHART,J.FURRER,A.DEHNER,H.KESSLERTITL SOLUTION STRUCTURE AND BINDING STUDIES OF THE P63TITL 2 DNA BINDING DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2vge PPP1R13L crystal structure of the c-terminal region of human iaspp 2.1Å AUTH R.A.ROBINSON,X.LU,E.Y.JONES,C.SIEBOLDTITL BIOCHEMICAL AND STRUCTURAL STUDIES OF ASPPTITL 2 PROTEINS REVEAL DIFFERENTIAL BINDING TO P53, P63TITL 3 AND P73REF STRUCTURE V. 16 259 2008REFN ISSN 0969-2126PMID 18275817DOI 10.1016/J.STR.2007.11.012 Variant Set Distributions Mapped Variants
General Structure Information 2xvs TTC5 crystal structure of human ttc5 (strap) c-terminal ob domain 1.8Å AUTH C.J.ADAMS,A.C.PIKE,S.MANIAM,T.D.SHARPE,A.S.COUTTS,S.KNAPP,AUTH 2 N.B.LA THANGUE,A.N.BULLOCKTITL THE P53 COFACTOR STRAP EXHIBITS AN UNEXPECTED TPR MOTIF ANDTITL 2 OLIGONUCLEOTIDE-BINDING (OB)-FOLD STRUCTURE.REF PROC.NATL.ACAD.SCI.USA V. 109 3778 2012REFN ISSN 0027-8424PMID 22362889DOI 10.1073/PNAS.1113731109 Variant Set Distributions Mapped Variants
General Structure Information 3hf1 RRM2B crystal structure of human p53r2 2.6Å AUTH P.SMITH,B.ZHOU,N.HO,Y.C.YUAN,L.SU,S.C.TSAI,Y.YENTITL 2.6 A X-RAY CRYSTAL STRUCTURE OF HUMAN P53R2, ATITL 2 P53-INDUCIBLE RIBONUCLEOTIDE REDUCTASE .REF BIOCHEMISTRY V. 48 11134 2009REFN ISSN 0006-2960PMID 19728742DOI 10.1021/BI9001425 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2jng CUL7 solution structure of the cul7-cph domain from homo sapiens; northeast structural genomics consortium target ht1. -1.0Å AUTH L.KAUSTOV,J.LUKIN,A.LEMAK,S.DUAN,M.HO,R.DOHERTY,AUTH 2 L.Z.PENN,C.H.ARROWSMITHTITL THE CONSERVED CPH DOMAINS OF CUL7 AND PARC ARETITL 2 PROTEIN-PROTEIN INTERACTION MODULES THAT BIND THETITL 3 TETRAMERIZATION DOMAIN OF P53REF J.BIOL.CHEM. V. 282 11300 2007REFN ISSN 0021-9258PMID 17298945DOI 10.1074/JBC.M611297200 […]
General Structure Information 2ly4 TP53 hmgb1-facilitated p53 dna binding occurs via hmg-box/p53 transactivation domain interaction and is regulated by the acidic tail -1.0Å AUTH J.P.ROWELL,K.L.SIMPSON,K.STOTT,M.WATSON,J.O.THOMASTITL HMGB1-FACILITATED P53 DNA BINDING OCCURS VIA HMG-BOX/P53TITL 2 TRANSACTIVATION DOMAIN INTERACTION, REGULATED BY THE ACIDICTITL 3 TAIL.REF STRUCTURE V. 20 2014 2012REFN ISSN 0969-2126PMID 23063560DOI 10.1016/J.STR.2012.09.004 Variant Set Distributions Ripley’s […]
General Structure Information 4mzr TP53 crystal structure of a polypeptide p53 mutant bound to dna 2.9Å AUTH S.EMAMZADAH,L.TROPIA,I.VINCENTI,B.FALQUET,T.D.HALAZONETISTITL REVERSAL OF THE DNA-BINDING-INDUCED LOOP L1 CONFORMATIONALTITL 2 SWITCH IN AN ENGINEERED HUMAN P53 PROTEIN.REF J.MOL.BIOL. V. 426 936 2014REFN ISSN 0022-2836PMID 24374182DOI 10.1016/J.JMB.2013.12.020 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]