General Structure Information
| PDB ID | 3hf1 |
| HGNC Gene Label(s) | RRM2B |
| Structure Name | crystal structure of human p53r2 |
| Resolution | 2.6Å |
| Reference | AUTH P.SMITH,B.ZHOU,N.HO,Y.C.YUAN,L.SU,S.C.TSAI,Y.YENTITL 2.6 A X-RAY CRYSTAL STRUCTURE OF HUMAN P53R2, ATITL 2 P53-INDUCIBLE RIBONUCLEOTIDE REDUCTASE .REF BIOCHEMISTRY V. 48 11134 2009REFN ISSN 0006-2960PMID 19728742DOI 10.1021/BI9001425 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 286 |
| Number Of SNVs | 56 |
| Number Of Permutations | 27551 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.028 |
| p-value | 0.529 |
ClinVar
| Number Of Residues | 286 |
| Number Of SNVs | 17 |
| Number Of Permutations | 7793 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.162 |
| p-value | 0.305 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 56 |
| Number Of ClinVar SNVs | 17 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.052 |
| p-value | 0.542 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
