Assessment of Structural Intolerance and Durability
General Structure Information 2jzx PCBP2 pcbp2 kh1-kh2 domains -1.0Å AUTH Z.DU,S.FENN,R.TJHEN,T.JAMESTITL STRUCTURE OF THE FIRST AND SECOND KH DOMAINS OF HUMAN POLY-CTITL 2 BINDING PROTEIN-2 REVEALS INSIGHTS INTO ITS REGULATORYTITL 3 MECHANISMSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2kkt ATXN7L3 solution structure of the sca7 domain of human ataxin-7-l3 protein -1.0Å AUTH J.BONNET,Y.WANG,A.ATKINSON,J.KOFFLER,C.ROMIER,A.HAMICHE,AUTH 2 L.TORA,D.DEVYS,B.KIEFFERTITL HISTONE DEUBIQUITINATION BY SAGA IS MODULATED BY ANTITL 2 ATYPICAL ZINC FINGER DOMAIN OF ATAXIN-7REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3i4u DHX8 crystal structure analysis of a helicase associated domain 2.1Å AUTH D.KUDLINZKI,A.SCHMITT,H.CHRISTIAN,R.FICNERTITL STRUCTURAL ANALYSIS OF THE C-TERMINAL DOMAIN OF THETITL 2 SPLICEOSOMAL HELICASE PRP22REF BIOL.CHEM. V. 393 1131 2012REFN ISSN 1431-6730PMID 23096351DOI 10.1515/HSZ-2012-0158 Variant Set Distributions Mapped Variants
General Structure Information 2kgt PTK6 solution structure of sh3 domain of ptk6 -1.0Å AUTH W.LEE,S.KOTITL THE SOLUTION STRUCTURE OF SH3 DOMAIN OF PTK6REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4egc SIX1 crystal structure of mbp-fused human six1 bound to human eya2 eya domain 1.99Å AUTH A.N.PATRICK,J.H.CABRERA,A.L.SMITH,X.S.CHEN,H.L.FORD,R.ZHAOTITL STRUCTURE-FUNCTION ANALYSES OF THE HUMAN SIX1-EYA2 COMPLEXTITL 2 REVEAL INSIGHTS INTO METASTASIS AND BOR SYNDROME.REF NAT.STRUCT.MOL.BIOL. V. 20 447 2013REFN ISSN 1545-9993PMID 23435380DOI 10.1038/NSMB.2505 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 4egc SIX1 crystal structure of mbp-fused human six1 bound to human eya2 eya domain 1.99Å AUTH A.N.PATRICK,J.H.CABRERA,A.L.SMITH,X.S.CHEN,H.L.FORD,R.ZHAOTITL STRUCTURE-FUNCTION ANALYSES OF THE HUMAN SIX1-EYA2 COMPLEXTITL 2 REVEAL INSIGHTS INTO METASTASIS AND BOR SYNDROME.REF NAT.STRUCT.MOL.BIOL. V. 20 447 2013REFN ISSN 1545-9993PMID 23435380DOI 10.1038/NSMB.2505 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 4egc SIX1 crystal structure of mbp-fused human six1 bound to human eya2 eya domain 1.99Å AUTH A.N.PATRICK,J.H.CABRERA,A.L.SMITH,X.S.CHEN,H.L.FORD,R.ZHAOTITL STRUCTURE-FUNCTION ANALYSES OF THE HUMAN SIX1-EYA2 COMPLEXTITL 2 REVEAL INSIGHTS INTO METASTASIS AND BOR SYNDROME.REF NAT.STRUCT.MOL.BIOL. V. 20 447 2013REFN ISSN 1545-9993PMID 23435380DOI 10.1038/NSMB.2505 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 4ed5 ELAVL1 crystal structure of the two n-terminal rrm domains of hur complexed with rna 2.0Å AUTH H.WANG,F.ZENG,Q.LIU,H.LIU,Z.LIU,L.NIU,M.TENG,X.LITITL THE STRUCTURE OF THE ARE-BINDING DOMAINS OF HU ANTIGEN RTITL 2 (HUR) UNDERGOES CONFORMATIONAL CHANGES DURING RNA BINDING.REF ACTA CRYSTALLOGR.,SECT.D V. 69 373 2013REFN ISSN 0907-4449PMID 23519412DOI 10.1107/S0907444912047828 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3d1n POU6F1 structure of human brn-5 transcription factor in complex with corticotrophin-releasing hormone gene promoter 2.51Å AUTH J.H.PEREIRA,S.H.KIMTITL STRUCTURE OF HUMAN BRN-5 TRANSCRIPTION FACTOR INTITL 2 COMPLEX WITH CRH GENE PROMOTER.REF J.STRUCT.BIOL. V. 167 159 2009REFN ISSN 1047-8477PMID 19450691DOI 10.1016/J.JSB.2009.05.003 Variant Set Distributions Mapped Variants
General Structure Information 3a77 IRF3 the crystal structure of phosphorylated irf-3 1.8Å AUTH K.TAKAHASI,M.HORIUCHI,K.FUJII,S.NAKAMURA,N.N.NODA,AUTH 2 M.YONEYAMA,T.FUJITA,F.INAGAKITITL SER386 PHOSPHORYLATION OF TRANSCRIPTION FACTOR IRF-3 INDUCESTITL 2 DIMERIZATION AND ASSOCIATION WITH CBP/P300 WITHOUT OVERALLTITL 3 CONFORMATIONAL CHANGE.REF GENES CELLS V. 15 901 2010REFN ISSN 1356-9597PMID 20604809DOI 10.1111/J.1365-2443.2010.01427.X Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]