Assessment of Structural Intolerance and Durability
General Structure Information 1nbq F11R crystal structure of human junctional adhesion molecule type 1 2.9Å AUTH A.E.PROTA,J.A.CAMPBELL,P.SCHELLING,J.C.FORREST,AUTH 2 M.J.WATSON,T.R.PETERS,M.AURRAND-LIONS,B.A.IMHOF,AUTH 3 T.S.DERMODY,T.STEHLETITL CRYSTAL STRUCTURE OF HUMAN JUNCTIONAL ADHESIONTITL 2 MOLECULE 1: IMPLICATIONS FOR REOVIRUS BINDINGREF PROC.NATL.ACAD.SCI.USA V. 100 5366 2003REFN ISSN 0027-8424PMID 12697893DOI 10.1073/PNAS.0937718100 Variant Set Distributions Mapped Variants
General Structure Information 1v27 RIMS2 solution structure of the first c2 domain of rim2 -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN OF RIM2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1wfg RIMS2 pdz domain of human rim2b -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL PDZ DOMAIN OF HUMAN RIM2BREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2l5y STIM2 nmr structure of calcium-loaded stim2 ef-sam. -1.0Å AUTH L.ZHENG,P.B.STATHOPULOS,R.SCHINDL,G.Y.LI,C.ROMANIN,M.IKURATITL AUTO-INHIBITORY ROLE OF THE EF-SAM DOMAIN OF STIM PROTEINSTITL 2 IN STORE-OPERATED CALCIUM ENTRY.REF PROC.NATL.ACAD.SCI.USA V. 108 1337 2011REFN ISSN 0027-8424PMID 21217057DOI 10.1073/PNAS.1015125108 Variant Set Distributions Mapped Variants
General Structure Information 2pkd CD84 crystal structure of cd84: insite into slam family function 2.04Å AUTH Q.YAN,V.N.MALASHKEVICH,A.FEDOROV,E.FEDOROV,E.CAO,AUTH 2 J.W.LARY,J.L.COLE,S.G.NATHENSON,S.C.ALMOTITL STRUCTURE OF CD84 PROVIDES INSIGHT INTO SLAMTITL 2 FAMILY FUNCTION.REF PROC.NATL.ACAD.SCI.USA V. 104 10583 2007REFN ISSN 0027-8424PMID 17563375DOI 10.1073/PNAS.0703893104 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1kcg ULBP3 nkg2d in complex with ulbp3 2.6Å AUTH S.RADAEV,B.ROSTRO,A.G.BROOKS,M.COLONNA,P.D.SUNTITL CONFORMATIONAL PLASTICITY REVEALED BY THETITL 2 COCRYSTAL STRUCTURE OF NKG2D AND ITS CLASS ITITL 3 MHC-LIKE LIGAND ULBP3.REF IMMUNITY V. 15 1039 2001REFN ISSN 1074-7613PMID 11754823DOI 10.1016/S1074-7613(01)00241-2 Variant Set Distributions Mapped Variants
General Structure Information 3fzm BAG1 crystal structures of hsc70/bag1 in complex with small molecule inhibitors 2.3Å AUTH D.S.WILLIAMSON,J.BORGOGNONI,A.CLAY,Z.DANIELS,AUTH 2 P.DOKURNO,M.J.DRYSDALE,N.FOLOPPE,G.L.FRANCIS,AUTH 3 C.J.GRAHAM,R.HOWES,A.T.MACIAS,J.B.MURRAY,R.PARSONS,AUTH 4 T.SHAW,A.E.SURGENOR,L.TERRY,Y.WANG,M.WOOD,AUTH 5 A.J.MASSEYTITL NOVEL ADENOSINE-DERIVED INHIBITORS OF 70 KDA HEATTITL 2 SHOCK PROTEIN, DISCOVERED THROUGH STRUCTURE-BASEDTITL 3 DESIGNREF J.MED.CHEM. V. 52 1510 2009REFN ISSN 0022-2623PMID 19256508DOI 10.1021/JM801627A Variant Set Distributions Ripley’s K […]
General Structure Information 1uen NRCAM solution structure of the third fibronectin iii domain of human kiaa0343 protein -1.0Å AUTH K.MIYAMOTO,T.KIGAWA,F.HAYASHI,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD FIBRONECTIN IIITITL 2 DOMAIN OF HUMAN KIAA0343 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1uey NRCAM solution structure of the first fibronectin type iii domain of human kiaa0343 protein -1.0Å AUTH C.ZHAO,T.KIGAWA,Y.MUTO,S.KOSHIBA,N.TOCHIO,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST FIBRONECTIN TYPETITL 2 III DOMAIN OF HUMAN KIAA0343 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3r0n PVRL2 crystal structure of the immunoglobulin variable domain of nectin-2 1.3Å AUTH D.SAMANTA,U.A.RAMAGOPAL,R.RUBINSTEIN,V.VIGDOROVICH,AUTH 2 S.G.NATHENSON,S.C.ALMOTITL STRUCTURE OF NECTIN-2 REVEALS DETERMINANTS OF HOMOPHILIC ANDTITL 2 HETEROPHILIC INTERACTIONS THAT CONTROL CELL-CELL ADHESION.REF PROC.NATL.ACAD.SCI.USA V. 109 14836 2012REFN ISSN 0027-8424PMID 22927415DOI 10.1073/PNAS.1212912109 Variant Set Distributions Mapped Variants