Assessment of Structural Intolerance and Durability
General Structure Information 3n1g BOC crystal structure of dhhn bound to bocfn3 1.9Å AUTH J.M.KAVRAN,M.D.WARD,O.O.OLADOSU,S.MULEPATI,D.J.LEAHYTITL ALL MAMMALIAN HEDGEHOG PROTEINS INTERACT WITH CDO AND BOCTITL 2 IN A CONSERVED MANNER.REF J.BIOL.CHEM. 2010REFN ESSN 1083-351XPMID 20519495DOI 10.1074/JBC.M110.131680 Variant Set Distributions Mapped Variants
General Structure Information 2le9 S100A13 ragec2-s100a13 tetrameric complex -1.0Å AUTH S.G.RANI,S.K.MOHAN,C.YUTITL INTERACTION OF S100A13 WITH RECEPTOR FOR ADVANCED GLYCATIONTITL 2 END PRODUCTS (RAGE) C2 DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2kav SCN2A solution structure of the human voltage-gated sodium channel, brain isoform (nav1.2) -1.0Å AUTH V.Z.MILOUSHEV,J.A.LEVINE,M.A.ARBING,J.F.HUNT,G.S.PITT,AUTH 2 A.G.PALMERTITL SOLUTION STRUCTURE OF THE NAV1.2 C-TERMINAL EF-HAND DOMAIN.REF J.BIOL.CHEM. V. 284 6446 2009REFN ISSN 0021-9258PMID 19129176DOI 10.1074/JBC.M807401200 Variant Set Distributions Mapped Variants
General Structure Information 2wmn DOCK9 structure of the complex between dock9 and cdc42-gdp. 2.39Å AUTH J.YANG,Z.ZHANG,S.M.ROE,C.J.MARSHALL,D.BARFORDTITL ACTIVATION OF RHO GTPASES BY DOCK EXCHANGE FACTORSTITL 2 IS MEDIATED BY A NUCLEOTIDE SENSOR.REF SCIENCE V. 325 1398 2009REFN ISSN 0036-8075PMID 19745154DOI 10.1126/SCIENCE.1174468 Variant Set Distributions Mapped Variants
General Structure Information 2j67 TLR10 the tir domain of human toll-like receptor 10 (tlr10) 2.2Å AUTH T.NYMAN,P.STENMARK,S.FLODIN,I.JOHANSSON,M.HAMMARSTROM,AUTH 2 P.NORDLUNDTITL THE CRYSTAL STRUCTURE OF THE HUMAN TOLL-LIKE RECEPTOR 10TITL 2 CYTOPLASMIC DOMAIN REVEALS A PUTATIVE SIGNALING DIMER.REF J.BIOL.CHEM. V. 283 11861 2008REFN ISSN 0021-9258PMID 18332149DOI 10.1074/JBC.C800001200 Variant Set Distributions Mapped Variants
General Structure Information 3a2a HVCN1 the structure of the carboxyl-terminal domain of the human voltage- gated proton channel hv1 2.0Å AUTH S.J.LI,Q.ZHAO,Q.ZHOU,H.UNNO,Y.ZHAI,F.SUNTITL THE ROLE AND STRUCTURE OF THE CARBOXYL-TERMINAL DOMAIN OFTITL 2 THE HUMAN VOLTAGE-GATED PROTON CHANNEL HV1.REF J.BIOL.CHEM. V. 285 12047 2010REFN ISSN 0021-9258PMID 20147290DOI 10.1074/JBC.M109.040360 Variant Set Distributions Mapped Variants
General Structure Information 2kg5 ARAP3 nmr solution structure of arap3-sam -1.0Å AUTH M.LEONE,J.CELLITTI,M.PELLECCHIATITL THE SAM DOMAIN OF THE LIPID PHOSPHATASE SHIP2TITL 2 ADOPTS A COMMON MODEL TO INTERACT WITH ARAP3-SAMTITL 3 AND EPHA2-SAM.REF BMC STRUCT.BIOL. V. 9 59 2009REFN ESSN 1472-6807PMID 19765305DOI 10.1186/1472-6807-9-59 Variant Set Distributions Mapped Variants
General Structure Information 1yzg ARL5B structure of human adp-ribosylation factor-like 8 2.0Å AUTH A.ATANASSOVA,J.CHOE,C.ARROWSMITH,A.EDWARDS,AUTH 2 M.SUNDSTROM,A.BOCHKAREV,H.PARKTITL STRUCTURE OF HUMAN ADP-RIBOSYLATION FACTOR-LIKE 8REF TO BE PUBLISHED 2005REFN Variant Set Distributions Mapped Variants
General Structure Information 1zd9 ARL8A structure of human adp-ribosylation factor-like 10b 1.7Å AUTH A.ATANASSOVA,J.CHOE,C.ARROWSMITH,A.EDWARDS,AUTH 2 M.SUNDSTROM,A.BOCHKAREV,H.PARKTITL STRUCTURE OF HUMAN ADP-RIBOSYLATION FACTOR-LIKE 10BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2id5 LINGO1 crystal structure of the lingo-1 ectodomain 2.7Å AUTH L.MOSYAK,A.WOOD,B.DWYER,M.BUDDHA,M.JOHNSON,A.AULABAUGH,AUTH 2 X.ZHONG,E.PRESMAN,S.BENARD,K.KELLEHER,J.WILHELM,M.L.STAHL,AUTH 3 R.KRIZ,Y.GAO,Z.CAO,H.P.LING,M.N.PANGALOS,F.S.WALSH,AUTH 4 W.S.SOMERSTITL THE STRUCTURE OF THE LINGO-1 ECTODOMAIN, A MODULE IMPLICATEDTITL 2 IN CENTRAL NERVOUS SYSTEM REPAIR INHIBITION.REF J.BIOL.CHEM. V. 281 36378 2006REFN ISSN 0021-9258PMID 17005555DOI 10.1074/JBC.M607314200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]