Assessment of Structural Intolerance and Durability
General Structure Information 2p64 BTRC d domain of b-trcp 2.5Å AUTH X.TANG,S.ORLICKY,Z.LIN,A.WILLEMS,D.NECULAI,D.CECCARELLI,AUTH 2 F.MERCURIO,B.H.SHILTON,F.SICHERI,M.TYERSTITL SUPRAFACIAL ORIENTATION OF THE SCFCDC4 DIMER ACCOMMODATESTITL 2 MULTIPLE GEOMETRIES FOR SUBSTRATE UBIQUITINATION.REF CELL(CAMBRIDGE,MASS.) V. 129 1165 2007REFN ISSN 0092-8674PMID 17574027DOI 10.1016/J.CELL.2007.04.042 Variant Set Distributions Mapped Variants
General Structure Information 2pid YARS2 crystal structure of human mitochondrial tyrosyl-trna synthetase in complex with an adenylate analog 2.2Å AUTH L.BONNEFOND,M.FRUGIER,E.TOUZE,B.LORBER,C.FLORENTZ,R.GIEGE,AUTH 2 C.SAUTER,J.RUDINGER-THIRIONTITL CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL TYROSYL-TRNATITL 2 SYNTHETASE REVEALS COMMON AND IDIOSYNCRATIC FEATURES.REF STRUCTURE V. 15 1505 2007REFN ISSN 0969-2126PMID 17997975DOI 10.1016/J.STR.2007.09.018 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3l4g FARSA crystal structure of homo sapiens cytoplasmic phenylalanyl-trna synthetase 3.3Å AUTH I.FINAROV,N.MOOR,N.KESSLER,L.KLIPCAN,M.G.SAFROTITL STRUCTURE OF HUMAN CYTOSOLIC PHENYLALANYL-TRNA SYNTHETASE:TITL 2 EVIDENCE FOR KINGDOM-SPECIFIC DESIGN OF THE ACTIVE SITESTITL 3 AND TRNA BINDING PATTERNS.REF STRUCTURE V. 18 343 2010REFN ISSN 0969-2126PMID 20223217DOI 10.1016/J.STR.2010.01.002 Variant Set Distributions Mapped Variants
General Structure Information 2ekf AUP1 solution structure of ruh-075, a human cue domain -1.0Å AUTH A.Z.M.RUHUL MOMEN,H.HIROTA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF RUH-075, A HUMAN CUE DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4kc9 ARIH1 structure of hhari, a ring-ibr-ring ubiquitin ligase: autoinhibition of an ariadne-family e3 and insights into ligation mechanism 3.6Å AUTH D.M.DUDA,J.L.OLSZEWSKI,J.P.SCHUERMANN,I.KURINOV,D.J.MILLER,AUTH 2 A.NOURSE,A.F.ALPI,B.A.SCHULMANTITL STRUCTURE OF HHARI, A RING-IBR-RING UBIQUITIN LIGASE:TITL 2 AUTOINHIBITION OF AN ARIADNE-FAMILY E3 AND INSIGHTS INTOTITL 3 LIGATION MECHANISM.REF STRUCTURE V. 21 1030 2013REFN ISSN 0969-2126PMID 23707686DOI 10.1016/J.STR.2013.04.019 […]
General Structure Information 4mvt PIAS3 crystal structure of sumo e3 ligase pias3 2.3Å AUTH J.HU,A.DONG,Y.LI,W.TEMPEL,C.BOUNTRA,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,Y.TONG,STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL CRYSTAL STRUCTURE OF SUMO E3 LIGASE PIAS3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3evx UFC1 crystal structure of the human e2-like ubiquitin-fold modifier conjugating enzyme 1 (ufc1). northeast structural genomics consortium target hr41 2.54Å AUTH G.LIU,F.FOROUHAR,A.ELETSKY,H.S.ATREYA,J.M.ARAMINI,AUTH 2 R.XIAO,Y.J.HUANG,M.ABASHIDZE,J.SEETHARAMAN,J.LIU,AUTH 3 B.ROST,T.ACTON,G.T.MONTELIONE,J.F.HUNT,T.SZYPERSKITITL NMR AND X-RAY STRUCTURES OF HUMAN E2-LIKETITL 2 UBIQUITIN-FOLD MODIFIER CONJUGATING ENZYME 1TITL 3 (UFC1) REVEAL STRUCTURAL AND FUNCTIONALTITL 4 CONSERVATION IN THE METAZOAN UFM1-UBA5-UFC1TITL […]
General Structure Information 3u9j FBXL5 crystal structure of oxidized human fbxl5 hemerythrin like domain 1.6Å AUTH C.SHU,M.W.SUNG,M.D.STEWART,T.I.IGUMENOVA,X.TAN,P.LITITL THE STRUCTURAL BASIS OF IRON SENSING BY THE HUMAN F-BOXTITL 2 PROTEIN FBXL5.REF CHEMBIOCHEM V. 13 788 2012REFN ISSN 1439-4227PMID 22492618DOI 10.1002/CBIC.201200043 Variant Set Distributions Mapped Variants
General Structure Information 2lfe HECW2 solution nmr structure of n-terminal domain of human e3 ubiquitin- protein ligase hecw2, northeast structural genomics consortium (nesg) target ht6306a -1.0Å AUTH A.LEMAK,A.YEE,S.HOULISTON,M.GARCIA,S.CHITAYAT,S.DHE-PAGANON,AUTH 2 G.T.MONTELIONE,C.ARROWSMITHTITL NMR SOLUTION STRUCTURE OF N-TERMINAL DOMAIN OF E3 LIGASETITL 2 HECW2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2wfd LARS structure of the human cytosolic leucyl-trna synthetase editing domain 3.25Å AUTH E.SEIRADAKE,W.MAO,V.HERNANDEZ,S.J.BAKER,AUTH 2 J.J.PLATTNER,M.R.K.ALLEY,S.CUSACKTITL CRYSTAL STRUCTURES OF THE HUMAN AND FUNGALTITL 2 CYTOSOLIC LEUCYL-TRNA SYNTHETASE EDITING DOMAINS:TITL 3 A STRUCTURAL BASIS FOR THE RATIONAL DESIGN OFTITL 4 ANTIFUNGAL BENZOXABOROLES.REF J.MOL.BIOL. V. 390 196 2009REFN ISSN 0022-2836PMID 19426743DOI 10.1016/J.JMB.2009.04.073 Variant Set […]