Assessment of Structural Intolerance and Durability
General Structure Information 3keu PDXK crystal structure of human pl kinase with bound plp and atp 2.1Å AUTH A.K.GANDHI,F.N.MUSAYEV,M.K.SAFOTITL CRYSTAL STRUCTURE OF PL KINASE IN COMPLEX WITH MGATP ANDTITL 2 PLP: STRUCTURAL BASIS OF SEVERE INDUCED MGATP SUBSTRATETITL 3 INHIBITION OF THE ENZYMEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4c59 GAK structure of gak kinase in complex with nanobody (nbgak_4) 2.8Å AUTH A.CHAIKUAD,T.KEATES,C.VINCKE,M.KAUFHOLZ,M.ZENN,B.ZIMMERMANN,AUTH 2 C.GUTIERREZ,R.ZHANG,C.HATZOS-SKINTGES,A.JOACHIMIAK,AUTH 3 S.MUYLDERMANS,F.W.HERBERG,S.KNAPP,S.MULLERTITL STRUCTURE OF CYCLIN G-ASSOCIATED KINASE (GAK) TRAPPED INTITL 2 DIFFERENT CONFORMATIONS USING NANOBODIES.REF BIOCHEM.J. V. 459 59 2014REFN ISSN 0264-6021PMID 24438162DOI 10.1042/BJ20131399 Variant Set Distributions Mapped Variants
General Structure Information 2dyl MAP2K7 crystal structure of human mitogen-activated protein kinase kinase 7 activated mutant (s287d, t291d) 2.45Å AUTH M.KUKIMOTO-NIINO,T.TAKAGI,T.KAMINISHI,AUTH 2 T.UCHIKUBO-KAMO,T.TERADA,O.MATSUZAKI,M.SHIROUZU,AUTH 3 S.YOKOYAMATITL CRYSTAL STRUCTURE OF HUMAN MITOGEN-ACTIVATEDTITL 2 PROTEIN KINASE KINASE 7 ACTIVATED MUTANT (S287D,TITL 3 T291D)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]