General Structure Information 3hf1 RRM2B crystal structure of human p53r2 2.6Å AUTH P.SMITH,B.ZHOU,N.HO,Y.C.YUAN,L.SU,S.C.TSAI,Y.YENTITL 2.6 A X-RAY CRYSTAL STRUCTURE OF HUMAN P53R2, ATITL 2 P53-INDUCIBLE RIBONUCLEOTIDE REDUCTASE .REF BIOCHEMISTRY V. 48 11134 2009REFN ISSN 0006-2960PMID 19728742DOI 10.1021/BI9001425 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4h6j HIF1A identification of cys 255 in hif-1 as a novel site for development of covalent inhibitors of hif-1 /arnt pasb domain protein-protein interaction. 1.52Å AUTH R.CARDOSO,R.LOVE,C.L.NILSSON,S.BERGQVIST,D.NOWLIN,J.YAN,AUTH 2 K.K.LIU,J.ZHU,P.CHEN,Y.L.DENG,H.J.DYSON,M.J.GREIG,A.BROOUNTITL IDENTIFICATION OF CYS255 IN HIF-1 ALPHA AS A NOVEL SITE FORTITL 2 DEVELOPMENT OF COVALENT INHIBITORS OF HIF-1 ALPHA /ARNT PASBTITL 3 DOMAIN […]
General Structure Information 4b95 TCEB1 pvhl-elob-elob-elocc complex_(2s,4r)-1-(2-chlorophenyl)carbonyl-n-[ (4-chlorophenyl)methyl]-4-oxidanyl-pyrrolidine-2-carboxamide bound 2.8Å AUTH D.L.BUCKLEY,J.L.GUSTAFSON,I.VAN MOLLE,A.G.ROTH,H.S.TAE,AUTH 2 P.C.GAREISS,W.L.JORGENSEN,A.CIULLI,C.M.CREWSTITL SMALL-MOLECULE INHIBITORS OF THE INTERACTION BETWEEN THE E3TITL 2 LIGASE VHL AND HIF1ALPHAREF ANGEW.CHEM.INT.ED.ENGL. V. 51 11463 2012REFN ISSN 1433-7851PMID 23065727DOI 10.1002/ANIE.201206231 Variant Set Distributions Mapped Variants
General Structure Information 4b95 TCEB1 pvhl-elob-elob-elocc complex_(2s,4r)-1-(2-chlorophenyl)carbonyl-n-[ (4-chlorophenyl)methyl]-4-oxidanyl-pyrrolidine-2-carboxamide bound 2.8Å AUTH D.L.BUCKLEY,J.L.GUSTAFSON,I.VAN MOLLE,A.G.ROTH,H.S.TAE,AUTH 2 P.C.GAREISS,W.L.JORGENSEN,A.CIULLI,C.M.CREWSTITL SMALL-MOLECULE INHIBITORS OF THE INTERACTION BETWEEN THE E3TITL 2 LIGASE VHL AND HIF1ALPHAREF ANGEW.CHEM.INT.ED.ENGL. V. 51 11463 2012REFN ISSN 1433-7851PMID 23065727DOI 10.1002/ANIE.201206231 Variant Set Distributions Mapped Variants
General Structure Information 3hr4 NOS2 human inos reductase and calmodulin complex 2.5Å AUTH C.XIA,I.MISRA,T.IYANAKI,J.J.K.KIMTITL REGULATION OF INTERDOMAIN INTERACTIONS BY CAM IN INDUCIBLETITL 2 NITRIC OXIDE SYNTHASEREF J.BIOL.CHEM. 2009REFN ESSN 1083-351X Variant Set Distributions Mapped Variants