Assessment of Structural Intolerance and Durability
General Structure Information 1yjr ATP7A solution structure of the apo form of the sixth soluble domain a69p mutant of menkes protein -1.0Å AUTH L.BANCI,I.BERTINI,F.CANTINI,M.MIGLIARDI,A.ROSATO,AUTH 2 S.WANGTITL AN ATOMIC-LEVEL INVESTIGATION OF THETITL 2 DISEASE-CAUSING A629P MUTANT OF THE MENKESTITL 3 PROTEIN, ATP7AREF J.MOL.BIOL. V. 352 409 2005REFN ISSN 0022-2836PMID 16083905DOI 10.1016/J.JMB.2005.07.034 Variant Set Distributions Mapped Variants
General Structure Information 1yjr ATP7A solution structure of the apo form of the sixth soluble domain a69p mutant of menkes protein -1.0Å AUTH L.BANCI,I.BERTINI,F.CANTINI,M.MIGLIARDI,A.ROSATO,AUTH 2 S.WANGTITL AN ATOMIC-LEVEL INVESTIGATION OF THETITL 2 DISEASE-CAUSING A629P MUTANT OF THE MENKESTITL 3 PROTEIN, ATP7AREF J.MOL.BIOL. V. 352 409 2005REFN ISSN 0022-2836PMID 16083905DOI 10.1016/J.JMB.2005.07.034 Variant Set Distributions Mapped Variants
General Structure Information 1yjr ATP7A solution structure of the apo form of the sixth soluble domain a69p mutant of menkes protein -1.0Å AUTH L.BANCI,I.BERTINI,F.CANTINI,M.MIGLIARDI,A.ROSATO,AUTH 2 S.WANGTITL AN ATOMIC-LEVEL INVESTIGATION OF THETITL 2 DISEASE-CAUSING A629P MUTANT OF THE MENKESTITL 3 PROTEIN, ATP7AREF J.MOL.BIOL. V. 352 409 2005REFN ISSN 0022-2836PMID 16083905DOI 10.1016/J.JMB.2005.07.034 Variant Set Distributions Mapped Variants
General Structure Information 1q7l ACY1 zn-binding domain of the t347g mutant of human aminoacylase- i 1.4Å AUTH H.A.LINDNER,V.V.LUNIN,A.ALARY,R.HECKER,M.CYGLER,AUTH 2 R.MENARDTITL ESSENTIAL ROLES OF ZINC LIGATION AND ENZYMETITL 2 DIMERIZATION FOR CATALYSIS IN THETITL 3 AMINOACYLASE-1/M20 FAMILY.REF J.BIOL.CHEM. V. 278 44496 2003REFN ISSN 0021-9258PMID 12933810DOI 10.1074/JBC.M304233200 Variant Set Distributions Mapped Variants
General Structure Information 1q7l ACY1 zn-binding domain of the t347g mutant of human aminoacylase- i 1.4Å AUTH H.A.LINDNER,V.V.LUNIN,A.ALARY,R.HECKER,M.CYGLER,AUTH 2 R.MENARDTITL ESSENTIAL ROLES OF ZINC LIGATION AND ENZYMETITL 2 DIMERIZATION FOR CATALYSIS IN THETITL 3 AMINOACYLASE-1/M20 FAMILY.REF J.BIOL.CHEM. V. 278 44496 2003REFN ISSN 0021-9258PMID 12933810DOI 10.1074/JBC.M304233200 Variant Set Distributions Mapped Variants
General Structure Information 1q7l ACY1 zn-binding domain of the t347g mutant of human aminoacylase- i 1.4Å AUTH H.A.LINDNER,V.V.LUNIN,A.ALARY,R.HECKER,M.CYGLER,AUTH 2 R.MENARDTITL ESSENTIAL ROLES OF ZINC LIGATION AND ENZYMETITL 2 DIMERIZATION FOR CATALYSIS IN THETITL 3 AMINOACYLASE-1/M20 FAMILY.REF J.BIOL.CHEM. V. 278 44496 2003REFN ISSN 0021-9258PMID 12933810DOI 10.1074/JBC.M304233200 Variant Set Distributions Mapped Variants
General Structure Information 2qv2 OCRL a role of the lowe syndrome protein ocrl in early steps of the endocytic pathway 2.4Å AUTH K.S.ERDMANN,Y.MAO,H.J.MCCREA,R.ZONCU,S.LEE,AUTH 2 S.PARADISE,J.MODREGGER,D.BIEMESDERFER,D.TOOMRE,AUTH 3 P.DE CAMILLITITL A ROLE OF THE LOWE SYNDROME PROTEIN OCRL IN EARLYTITL 2 STEPS OF THE ENDOCYTIC PATHWAYREF DEV.CELL V. 13 377 2007REFN ISSN 1534-5807PMID 17765681DOI 10.1016/J.DEVCEL.2007.08.004 Variant Set […]
General Structure Information 2qv2 OCRL a role of the lowe syndrome protein ocrl in early steps of the endocytic pathway 2.4Å AUTH K.S.ERDMANN,Y.MAO,H.J.MCCREA,R.ZONCU,S.LEE,AUTH 2 S.PARADISE,J.MODREGGER,D.BIEMESDERFER,D.TOOMRE,AUTH 3 P.DE CAMILLITITL A ROLE OF THE LOWE SYNDROME PROTEIN OCRL IN EARLYTITL 2 STEPS OF THE ENDOCYTIC PATHWAYREF DEV.CELL V. 13 377 2007REFN ISSN 1534-5807PMID 17765681DOI 10.1016/J.DEVCEL.2007.08.004 Variant Set […]
General Structure Information 2qv2 OCRL a role of the lowe syndrome protein ocrl in early steps of the endocytic pathway 2.4Å AUTH K.S.ERDMANN,Y.MAO,H.J.MCCREA,R.ZONCU,S.LEE,AUTH 2 S.PARADISE,J.MODREGGER,D.BIEMESDERFER,D.TOOMRE,AUTH 3 P.DE CAMILLITITL A ROLE OF THE LOWE SYNDROME PROTEIN OCRL IN EARLYTITL 2 STEPS OF THE ENDOCYTIC PATHWAYREF DEV.CELL V. 13 377 2007REFN ISSN 1534-5807PMID 17765681DOI 10.1016/J.DEVCEL.2007.08.004 Variant Set […]
General Structure Information 1ism BST1 crystal structure analysis of bst-1/cd157 complexed with nicotinamide 3.0Å AUTH S.YAMAMOTO-KATAYAMA,M.ARIYOSHI,K.ISHIHARA,T.HIRANO,AUTH 2 H.JINGAMI,K.MORIKAWATITL CRYSTALLOGRAPHIC STUDIES ON HUMAN BST-1/CD157 WITHTITL 2 ADP-RIBOSYL CYCLASE AND NAD GLYCOHYDROLASE ACTIVITIES.REF J.MOL.BIOL. V. 316 711 2002REFN ISSN 0022-2836PMID 11866528DOI 10.1006/JMBI.2001.5386 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants