General Structure Information
| PDB ID | 2qv2 |
| HGNC Gene Label(s) | OCRL |
| Structure Name | a role of the lowe syndrome protein ocrl in early steps of the endocytic pathway |
| Resolution | 2.4Å |
| Reference | AUTH K.S.ERDMANN,Y.MAO,H.J.MCCREA,R.ZONCU,S.LEE,AUTH 2 S.PARADISE,J.MODREGGER,D.BIEMESDERFER,D.TOOMRE,AUTH 3 P.DE CAMILLITITL A ROLE OF THE LOWE SYNDROME PROTEIN OCRL IN EARLYTITL 2 STEPS OF THE ENDOCYTIC PATHWAYREF DEV.CELL V. 13 377 2007REFN ISSN 1534-5807PMID 17765681DOI 10.1016/J.DEVCEL.2007.08.004 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 305 |
| Number Of SNVs | 36 |
| Number Of Permutations | 28457 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.083 |
| p-value | 0.805 |
COSMIC
| Number Of Residues | 305 |
| Number Of SNVs | 4 |
| Number Of Permutations | 488 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.333 |
| p-value | 0.442 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 36 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.167 |
| p-value | 0.819 |